Cancer cachexia is a complex disorder that is driven by inflammation and metabolic
imbalances, resulting in extreme weight loss. Adipose tissue, a main player in cancer …

Advanced cancer patients exhibit cachexia, a condition characterized by a significant
reduction in the body weight predominantly from loss of skeletal muscle and adipose tissue …

Neurotrophic factors (NTFs) are involved in the pathophysiology of neurological disorders
such as dementia, stroke and traumatic brain injury (TBI), and constitute molecular targets of …

Medicine has benefited greatly from the development of monoclonal antibody (mAb)
technology. First-generation mAbs have seen significant success in the treatment of major …

Cancer cachexia often occurs in malignant tumors and is a multifactorial and complex
symptom characterized by wasting of skeletal muscle and adipose tissue, resulting in weight …

Cancer-associated cachexia (CAC) is a major characteristic of advanced cancer, associates
with almost all types of cancer. Recent studies have found that lipopenia is an important …

Tumor necrosis factor-α (TNF-α) is a pluripotent mediator of pro-inflammatory and
antimicrobial defense mechanisms and a regulator of lymphoid organ development …

Simple Summary As a result of increasing demand for the pleiotropic cytokine TNF-α,
recombinant human TNF-α protein with appropriate bioactivities was produced in several …

Background Lung cancer is characterized by high-risk and high mortality, among which non-
small cell lung cancer (NSCLC) conquers a dominant position. Previous studies have …

Background: peritumoral collateral vessels adjacent to renal cell carcinoma (RCC) can be
encountered in clinical practice. Cancer cachexia is defined as a decrease of adipose and …