Membrane-interacting antifungal peptides

C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Antifungal peptides as therapeutic agents

M Fernández de Ullivarri, S Arbulu… - Frontiers in Cellular …, 2020 - frontiersin.org
Fungi have been used since ancient times in food and beverage-making processes and,
more recently, have been harnessed for the production of antibiotics and in processes of …

Antimicrobial Peptides with Anti-Candida Activity

A Perez-Rodriguez, E Eraso, G Quindós… - International journal of …, 2022 - mdpi.com
Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is
the most usual, presenting a high morbidity and mortality. Candida albicans remains the …

Characterization of a fungal competition factor: production of a conidial cell-wall associated antifungal peptide

S Tong, M Li, NO Keyhani, Y Liu, M Yuan, D Lin… - PLoS …, 2020 - journals.plos.org
Competition is one of the fundamental driving forces of natural selection. Beauveria
bassiana is a soil and plant phylloplane/root fungus capable of parasitizing insect hosts. Soil …

Mapping of the lipid-binding regions of the antifungal protein NFAP2 by exploiting model membranes

O Pavela, T Juhász, L Tóth, A Czajlik… - Journal of Chemical …, 2024 - ACS Publications
Fungal infections with high mortality rates represent an increasing health risk. The
Neosartorya (Aspergillus) fischeri antifungal protein 2 (NFAP2) is a small, cysteine-rich …

Potential of Antifungal Proteins (AFPs) to Control Penicillium Postharvest Fruit Decay

M Gandía, A Kakar, M Giner-Llorca, J Holzknecht… - Journal of Fungi, 2021 - mdpi.com
Penicillium phytopathogenic species provoke severe postharvest disease and economic
losses. Penicillium expansum is the main pome fruit phytopathogen while Penicillium …

Efficient production of antifungal proteins in plants using a new transient expression vector derived from tobacco mosaic virus

X Shi, T Cordero, S Garrigues… - Plant biotechnology …, 2019 - Wiley Online Library
Fungi that infect plants, animals or humans pose a serious threat to human health and food
security. Antifungal proteins (AFP s) secreted by filamentous fungi are promising …

The combination of Neosartorya (Aspergillus) fischeri antifungal proteins with rationally designed γ-core peptide derivatives is effective for plant and crop protection

L Tóth, P Poór, A Ördög, G Váradi, A Farkas, C Papp… - BioControl, 2022 - Springer
Plant pathogenic fungi are responsible for enormous crop losses worldwide. Overcoming
this problem is challenging as these fungi can be highly resistant to approved chemical …

[HTML][HTML] Two small, cysteine-rich and cationic antifungal proteins from Penicillium chrysogenum: A comparative study of PAF and PAFB

A Huber, L Galgóczy, G Váradi, J Holzknecht… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The filamentous fungus Penicillium chrysogenum Q176 secretes the antimicrobial proteins
(AMPs) PAF and PAFB, which share a compact disulfide-bond mediated, β-fold structure …

Small, Cationic Antifungal Proteins from Filamentous Fungi Inhibit Candida albicans Growth in 3D Skin Infection Models

J Holzknecht, S Dubrac, S Hedtrich… - Microbiology …, 2022 - Am Soc Microbiol
The emerging resistance of human-pathogenic fungi to antifungal drugs urges the
development of alternative therapeutic strategies. The small, cationic antifungal proteins …