Systemic immunoglobulin light chain amyloidosis is a protein misfolding disease caused by the conversion of immunoglobulin light chains from their soluble functional states into highly …
M Heuser, SD Freeman… - Blood, The Journal …, 2021 - ashpublications.org
Measurable residual disease (MRD) is an important biomarker in acute myeloid leukemia (AML) that is used for prognostic, predictive, monitoring, and efficacy-response …
The prognostic value of minimal residual disease (MRD) for progression-free survival (PFS) and overall survival (OS) was evaluated in a large cohort of patients with multiple myeloma …
AD Cohen, AL Garfall, EA Stadtmauer… - The Journal of …, 2019 - Am Soc Clin Investig
BACKGROUND. CAR T cells are a promising therapy for hematologic malignancies. B cell maturation antigen (BCMA) is a rational target in multiple myeloma (MM). METHODS. We …
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical …
A Perrot, V Lauwers-Cances, J Corre… - Blood, The Journal …, 2018 - ashpublications.org
The introduction of novel agents has led to major improvements in clinical outcomes for patients with multiple myeloma. To shorten evaluation times for new treatments, health …
New approaches to stratify multiple myeloma patients based on prognosis and therapeutic decision-making, or prediction, are needed since patients are currently managed in a similar …
B Paiva, N Puig, MT Cedena, L Rosiñol… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Assessing measurable residual disease (MRD) has become standard with many tumors, but the clinical meaning of MRD in multiple myeloma (MM) remains uncertain …
H Goldschmidt, EK Mai, U Bertsch, R Fenk… - The Lancet …, 2022 - thelancet.com
Background Anti-CD38 monoclonal antibodies have consistently shown increased efficacy when added to standard of care for patients with multiple myeloma. We aimed to assess the …