The global tuberculosis burden remains substantial, with more than 10 million people newly
ill per year. Nevertheless, tuberculosis incidence has slowly declined over the past decade …

Executive summary Although health outcomes have improved in low-income and middle-
income countries (LMICs) in the past several decades, a new reality is at hand. Changing …

Executive summary Tuberculosis can be treated, prevented, and cured. Rapid, sustained
declines in tuberculosis deaths in many countries during the past 50 years provide …

Background Tuberculosis (TB) case notification rates are usually higher in men than in
women, but notification data are insufficient to measure sex differences in disease burden …

The cascade of care is a model for evaluating patient retention across sequential stages of
care required to achieve a successful treatment outcome. This approach was first used to …

Background Bringing reliable and accurate tuberculosis (TB) diagnosis closer to patients is
a key priority for global TB control. Molbio Diagnostics have developed the Truenat point-of …

The care cascade—which evaluates outcomes across stages of patient engagement in a
health system—is an important framework for assessing quality of tuberculosis (TB) care. In …

Background The performance of laboratory tests to diagnose pulmonary tuberculosis is
dependent on the quality of the sputum sample tested. The relative merits of sputum …

Background Decentralised molecular testing for tuberculosis could reduce missed
diagnoses and losses to follow-up in high-burden settings. The aim of this study was to …

Background Individuals who test positive for active tuberculosis (TB) but do not initiate
treatment present a challenge to TB programmes because they contribute to ongoing …