RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Mechanistic target of rapamycin (mTOR) is a protein kinase regulating cell growth, survival,
metabolism, and immunity. mTOR is usually assembled into several complexes such as …

Many eukaryotic protein-coding genes are able to generate exonic circular RNAs. Most of
these covalently linked transcripts are expressed at low levels, but some accumulate to …

Membraneless organelles involved in RNA processing are biomolecular condensates
assembled by phase separation. Despite the important role of intrinsically disordered protein …

Abstract The mRNA SARS-CoV-2 vaccines were brought to market in response to the public
health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious …

After three decades of the amazing progress made on molecular studies of plant–microbe
interactions (MPMI), we have begun to ask ourselves" what are the major questions still …

It was thought until the 1990s that the eukaryotic translation machinery was unable to
translate a circular RNA. However internal ribosome entry sites (IRESs) and m6A-induced …

Circular RNAs a kind of covalently closed RNA and widely expressed in eukaryotes.
CircRNAs are involved in a variety of physiological and pathological processes, but their …

Organisms regulate gene expression to produce essential proteins for numerous biological
processes, from growth and development to stress responses. Transcription and translation …

Cellular stress is an intrinsic part of cell physiology that underlines cell survival or death. The
ability of mammalian cells to regulate global protein synthesis (aka translational control) …