For two decades the scientific community has sought to understand why some people clear
hepatitis C virus (HCV) and others do not. Recently, several large genome-wide association …

Precision medicine based upon molecular testing is heralded as a revolution in how cancer
is prevented, diagnosed, and treated. Large efforts across the world aim to conduct …

Hepatitis C virus (HCV) is an RNA virus that affects> 180 million individuals worldwide with a
high propensity for chronic infection. Children with HCV infection differ from adults in several …

Background: Hepatitis A virus cellular receptor 1 (HAVcR-1) may function as part of the
regulatory apparatus for tight junction in human endothelial cells, and is overexpressed in …

The discovery of the interferon‐lambda (IFN‐λ) family has considerably contributed to our
understanding of the role of interferon not only in viral infections but also in cancer. IFN‐λ …

The outcome of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are
heterogeneous, ranging from an asymptomatic self-limiting infection to cirrhosis and …

Host genetic variation may affect the outcome of chronic viral hepatitides, favoring viral
clearance and/or modulating the inflammatory response to persistent infection. Our aims …

Detecting overexpression of cancer biomarkers is an excellent tool for diagnostic/prognostic
and follow-up of patients with cancer or their response to treatment. This work illustrates the …

The combined regulation of a network of inhibitory and activating T cell receptors may be a
critical step in the development of chronic HCV infection. Ex vivo HCV MHC class I+ II …

Abstract Background Hepatitis C virus (HCV) infection is the major cause of hepatocellular
carcinoma (HCC), a common primary liver malignancy, and the third leading cause of …