Background The World Health Organization recommends uncomplicated P. falciparum
malaria is treated using Artemisinin‐based Combination Therapy (ACT). This review aims to …

Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Background Efficient allocation of resources to intervene against malaria requires a detailed
understanding of the contemporary spatial distribution of malaria risk. It is exactly 40 y since …

We have analyzed the in vitro chemosensitivity profiles of 115 Kenyan isolates for
chloroquine (CQ), piperaquine, lumefantrine (LM), and dihydroartemisinin in association …

Background. In treating malaria in Uganda, artemether-lumefantrine (AL) has been
associated with a lower risk of recurrent parasitemia, compared with artesunate …

Background Individual patient data (IPD) meta‐analysis is the gold standard. Aggregate
data (AD) and IPD can be combined using conventional pairwise meta‐analysis when IPD …

Abstract Current World Health Organization (WHO) guidelines for the treatment of
uncomplicated falciparum malaria recommend the use of artemisinin-based combination …

Malaria is a disease that affects thousands of people around the world every year. Its
pathogenesis is associated with the production of reactive oxygen and nitrogen species …

Abstract Background: The Lives Saved Tool (LiST) model was developed to estimate the
impact of the scale-up of child survival interventions on child mortality. New advances in …

Background Chlorproguanil− dapsone− artesunate (CDA) was developed as an affordable,
simple, fixed-dose artemisinin-based combination therapy for use in Africa. This trial was a …