MicroRNA-206 in human cancer: mechanistic and clinical perspectives

LB Khasraghi, M Nouri, M Vazirzadeh, N Hashemipour… - Cellular …, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), small non-coding RNAs approximately 20–25 nt in length,
play important roles via directly binding to the corresponding 3′ UTR of target mRNAs …

Annexin A protein family: Focusing on the occurrence, progression and treatment of cancer

H Zhang, Z Zhang, T Guo, G Chen, G Liu… - Frontiers in Cell and …, 2023 - frontiersin.org
The annexin A (ANXA) protein family is a well-known tissue-specific multigene family that
encodes Ca2+ phospholipid-binding proteins. A considerable amount of literature is …

[HTML][HTML] Explainable artificial intelligence to predict and identify prostate cancer tissue by gene expression

A Ramírez-Mena, E Andrés-León… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective: Prostate cancer is one of the most prevalent forms of
cancer in men worldwide. Traditional screening strategies such as serum PSA levels, which …

AnnexinA6: a potential therapeutic target gene for extracellular matrix mineralization

J Yang, T Pei, G Su, P Duan, X Liu - Frontiers in Cell and …, 2023 - frontiersin.org
The mineralization of the extracellular matrix (ECM) is an essential and crucial process for
physiological bone formation and pathological calcification. The abnormal function of ECM …

(20S) Ginsenoside Rh2 inhibits STAT3/VEGF signaling by targeting annexin A2

YS Wang, C Chen, SY Zhang, Y Li, YH Jin - International Journal of …, 2021 - mdpi.com
Signal transducers and activators of transcription 3 (STAT3) acts as a transcriptional signal
transducer, converting cytokine stimulation into specific gene expression. In tumor cells …

PTEN protein phosphatase activity is not required for tumour suppression in the mouse prostate

HM Wise, A Harris, N Kriplani, A Schofield, H Caldwell… - Biomolecules, 2022 - mdpi.com
Loss PTEN function is one of the most common events driving aggressive prostate cancers
and biochemically, PTEN is a lipid phosphatase which opposes the activation of the …

[HTML][HTML] The multifaceted role of extracellular vesicles in prostate cancer-a review

DP Jain, YH Dinakar, H Kumar, R Jain… - Cancer Drug …, 2023 - ncbi.nlm.nih.gov
Prostate cancer is the second most prominent form of cancer in men and confers the highest
mortality after lung cancer. The term “extracellular vesicles” refers to minute endosomal …

Higher expression of annexin A2 in metastatic bladder urothelial carcinoma promotes migration and invasion

C Guo, R Trivedi, AK Tripathi, RR Nandy, DC Wagner… - Cancers, 2022 - mdpi.com
Simple Summary Bladder urothelial carcinoma (BLCA) arises from basal cells that develop
dysplasia and carcinoma in situ and, if unchecked, progress to invasion and metastases …

Identifying critical protein‑coding genes and long non‑coding RNAs in non‑functioning pituitary adenoma recurrence

J Guo, Q Fang, Y Liu, W Xie, Y Zhang… - Oncology …, 2021 - spandidos-publications.com
Non‑functioning pituitary adenoma (NFPA) is a very common type of intracranial tumor.
Monitoring and predicting the postoperative recurrence of NFPAs is difficult, as these …

Analysis of transcriptomic data reveals the landscape of cholesterol metabolism in prostate cancer and impact of related signature on survival

JX Sun, Y An, MY Xu, SY Ma, CQ Liu, JZ Xu, QD Xia… - Discover Oncology, 2024 - Springer
Background Cholesterol metabolism is essential for the development and progression of
prostate cancer (PCa). Our previous study provided a new insight of cholesterol metabolism …