Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

Background: In 2004, the term acute kidney injury (AKI) was introduced with the intention of
broadening our understanding of rapid declines in renal function and to replace the …

Developing new therapeutic drugs to prevent ischemia/reperfusion (I/R)-induced renal
injuries is highly pursued. Liposomal encapsulation of spironolactone (SP) as a …

Background: The present study aimed to investigate whether the inflammatory and
antioxidant lycopene has a therapeutic effect against renal ischemia/reperfusion (I/R) injury …

Abstract Resumen Context: Almost one year after the onset of COVID-19 pandemic in
Wuhan, China and still no specific therapy has emerged, counting millions of dead …

Although methylene blue (MB) has showed strong antioxidant effect, its effect related with
heme oxygenase-1 (HO-1) is still unclear. Thus, we investigated the effects of MB on HO-1 …

Different diseases or xenobiotics could cause cholestasis. The only promising treatment for
this disease is the identification of its etiology or liver transplantation in severe cases …

Objective. This study was aimed to investigate the protective effect of methylene blue against
lung injury induced by reperfusion of ischemic hindlimb in a rat model. Methods. Twenty …

Introduction Impaired mitochondrial function is a key factor attributing to the lung ischemia
reperfusion injury (LIRI). Methylene blue (MB) has been reported to attenuate brain and …

Introduction: Reactive oxygen species (ROS) are the main factors in pathogenesis of renal
ischemia-reperfusion (I/R) injury. Objectives: The aim of this study was to evaluate the …