[HTML][HTML] Protein–protein interaction prediction with deep learning: A comprehensive review

F Soleymani, E Paquet, H Viktor, W Michalowski… - Computational and …, 2022 - Elsevier
Most proteins perform their biological function by interacting with themselves or other
molecules. Thus, one may obtain biological insights into protein functions, disease …

Hierarchical graph learning for protein–protein interaction

Z Gao, C Jiang, J Zhang, X Jiang, L Li, P Zhao… - Nature …, 2023 - nature.com
Abstract Protein-Protein Interactions (PPIs) are fundamental means of functions and
signalings in biological systems. The massive growth in demand and cost associated with …

Multifaceted protein–protein interaction prediction based on Siamese residual RCNN

M Chen, CJT Ju, G Zhou, X Chen, T Zhang… - …, 2019 - academic.oup.com
Motivation Sequence-based protein–protein interaction (PPI) prediction represents a
fundamental computational biology problem. To address this problem, extensive research …

LightGBM-PPI: Predicting protein-protein interactions through LightGBM with multi-information fusion

C Chen, Q Zhang, Q Ma, B Yu - Chemometrics and Intelligent Laboratory …, 2019 - Elsevier
Protein-protein interactions (PPIs) play an important role in cell life activities such as
transcriptional regulation, signal transduction and drug signal transduction. The study of …

Learning spatial structures of proteins improves protein–protein interaction prediction

B Song, X Luo, X Luo, Y Liu, Z Niu… - Briefings in …, 2022 - academic.oup.com
Spatial structures of proteins are closely related to protein functions. Integrating protein
structures improves the performance of protein–protein interaction (PPI) prediction …

Predicting protein–protein interactions through sequence-based deep learning

S Hashemifar, B Neyshabur, AA Khan, J Xu - Bioinformatics, 2018 - academic.oup.com
Motivation High-throughput experimental techniques have produced a large amount of
protein–protein interaction (PPI) data, but their coverage is still low and the PPI data is also …

DeepPPI: boosting prediction of protein–protein interactions with deep neural networks

X Du, S Sun, C Hu, Y Yao, Y Yan… - Journal of chemical …, 2017 - ACS Publications
The complex language of eukaryotic gene expression remains incompletely understood.
Despite the importance suggested by many proteins variants statistically associated with …

Predicting protein-protein interactions via multivariate mutual information of protein sequences

Y Ding, J Tang, F Guo - BMC bioinformatics, 2016 - Springer
Abstract Background Protein-protein interactions (PPIs) are central to a lot of biological
processes. Many algorithms and methods have been developed to predict PPIs and protein …

Mape-ppi: Towards effective and efficient protein-protein interaction prediction via microenvironment-aware protein embedding

L Wu, Y Tian, Y Huang, S Li, H Lin, NV Chawla… - arXiv preprint arXiv …, 2024 - arxiv.org
Protein-Protein Interactions (PPIs) are fundamental in various biological processes and play
a key role in life activities. The growing demand and cost of experimental PPI assays require …

Using Weighted Sparse Representation Model Combined with Discrete Cosine Transformation to Predict Protein‐Protein Interactions from Protein Sequence

YA Huang, ZH You, X Gao, L Wong… - BioMed research …, 2015 - Wiley Online Library
Increasing demand for the knowledge about protein‐protein interactions (PPIs) is promoting
the development of methods for predicting protein interaction network. Although high …