Colicins are proteins produced by and toxic for some strains of Escherichia coli. They are
produced by strains of E. coli carrying a colicinogenic plasmid that bears the genetic …

To survive in rapidly changing environmental conditions, bacteria have evolved a diverse
set of regulatory pathways that govern various adaptive responses. Recent research has …

We developed a reliable and flexible green fluorescent protein (GFP)-based system for
measuring gene expression in individual bacterial cells. Until now, most systems have relied …

The use of nucleases as toxins for defense, offense or addiction of selfish elements is widely
encountered across all life forms. Using sensitive sequence profile analysis methods, we …

In Bacillus subtilis competence for genetic transformation develops only in a subpopulation
of cells in an isogenic culture. The molecular mechanisms underlying this phenotypic …

Bacteria often produce antimicrobial toxins to compete in microbial communities. Here we
identify a family of broad-spectrum peptide toxins, named bacteroidetocins, produced by …

0001. This application claims the benefit under 35 USC S119 (e) of US Provisional
Application Ser. No. 61/307,301, entitled “PATHOGEN SENSE AND DESTROY filed on Feb …

Almost all currently employed analytical “-omics” methods provide data that are averaged
over an entire cell population, but even genetically identical cells exposed to the same …

Persisters are the minor subpopulation of bacterial cells that lack alleles conferring
resistance to a specific bactericidal antibiotic but can survive otherwise lethal concentrations …

Behaviors that cause the death of an actor are typically strongly disfavored by natural
selection, and yet many bacteria undergo cell lysis to release anti-competitor toxins [1–5] …