Revealing lncRNA structures and interactions by sequencing-based approaches

X Qian, J Zhao, PY Yeung, QC Zhang… - Trends in biochemical …, 2019 - cell.com
Long noncoding RNAs (lncRNAs) have emerged as significant players in almost every level
of gene function and regulation. Thus, characterizing the structures and interactions of …

MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside

M Ratti, A Lampis, M Ghidini, M Salati, MB Mirchev… - Targeted …, 2020 - Springer
Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …

Long non-coding RNAs and complex diseases: from experimental results to computational models

X Chen, CC Yan, X Zhang, ZH You - Briefings in bioinformatics, 2017 - academic.oup.com
LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …

Evolution to the rescue: using comparative genomics to understand long non-coding RNAs

I Ulitsky - Nature Reviews Genetics, 2016 - nature.com
Long non-coding RNAs (lncRNAs) have emerged in recent years as major players in a
multitude of pathways across species, but it remains challenging to understand which of …

NONCODE 2016: an informative and valuable data source of long non-coding RNAs

Y Zhao, H Li, S Fang, Y Kang, W Wu, Y Hao… - Nucleic acids …, 2016 - academic.oup.com
Abstract NONCODE (http://www. bioinfo. org/noncode/) is an interactive database that aims
to present the most complete collection and annotation of non-coding RNAs, especially long …

Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

Interaction and cross-talk between non-coding RNAs

S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …

Lnc2Cancer: a manually curated database of experimentally supported lncRNAs associated with various human cancers

S Ning, J Zhang, P Wang, H Zhi, J Wang… - Nucleic acids …, 2016 - academic.oup.com
Abstract Lnc2Cancer (http://www. bio-bigdata. net/lnc2cancer) is a manually curated
database of cancer-associated long non-coding RNAs (lncRNAs) with experimental support …

lncRNASNP2: an updated database of functional SNPs and mutations in human and mouse lncRNAs

YR Miao, W Liu, Q Zhang, AY Guo - Nucleic acids research, 2018 - academic.oup.com
Long non-coding RNAs (lncRNAs) are emerging as important regulators in different
biological processes through various ways. Because the related data, especially mutations …

A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3

Y Zhou, Y Shao, W Hu, J Zhang, Y Shi… - Cell Death & …, 2023 - nature.com
Although radiotherapy is an essential modality in the treatment of colorectal cancer (CRC),
the incidence of radioresistance remains high clinically. Long noncoding RNAs (lncRNAs) …