Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Advances in atherosclerosis imaging technology and research have provided a range of
diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular …

The realization of hybrid optics could be one of the best ways to fulfill the technological
requirements of compact, light-weight, and multi-functional optical systems for modern …

Cumulative evidence from histology-based studies demonstrate that the currently available
intravascular imaging techniques have fundamental limitations that do not allow complete …

Objectives: The authors present the clinical imaging of human coronary arteries in vivo using
a multimodality optical coherence tomography (OCT) and near-infrared autofluorescence …

Aims Emotional stress is associated with future cardiovascular events. However, the
mechanistic linkage of brain emotional neural activity with acute plaque instability is not fully …

While coronary atherosclerosis is a leading cause of mortality, evaluation of coronary
lesions was previously limited to either indirect angiographic assessment of the lumen …

Indocyanine green (ICG) is the only near-infrared dye approved by the US Food and Drug
Administration for clinical use. When injected in blood, ICG binds primarily to plasma …

Rationale: Inflammation plays a pivotal role in the pathogenesis of the acute coronary
syndrome. Detecting plaques with high inflammatory activity and specifically treating those …

Objectives: This study sought to determine whether indocyanine green (ICG)–enhanced
near-infrared fluorescence (NIRF) imaging can illuminate high-risk histologic plaque …