The developmental origins of health and disease theory is based on evidence that a
suboptimal environment during fetal and neonatal development can significantly impact the …

The endothelium controls vascular tone not only by releasing various vasoactive substances
but also by another pathway associated with the hyperpolarization of both endothelial and …

Rationale: Cardiac myocytes derived from pluripotent stem cells have demonstrated the
potential to mitigate damage of the infarcted myocardium and improve left ventricular …

To meet the need of a large quantity of hPSC-derived cardiomyocytes (CM) for pre-clinical
and clinical studies, a robust and scalable differentiation system for CM production is …

The ability to differentiate human pluripotent stem cells (hPSCs) into cardiomyocytes (CMs)
makes them an attractive source for repairing injured myocardium, disease modeling, and …

Background Studies exploring the relations between maternal stress and fetal development
show an association between increased maternal stress and adverse birth outcomes. A …

To elucidate the mechanisms underlying maternal undernutrition (MUN)-induced fetal
skeletal muscle growth impairment in cattle, the longissimus thoracis muscle of Japanese …

Maternal nutritional challenges during fetal and neonatal development result in
developmental programming of multiple offspring organ systems including brain maturation …

Key points Advanced maternal age increases the risk of pregnancy complications such as
fetal growth restriction, hypertension and premature birth. Offspring born from compromised …

Severe undernutrition and famine continue to be a worldwide concern, as cases have been
increasing in the past 5 years, particularly in developing countries. The occurrence of …