ROS, cell senescence, and novel molecular mechanisms in aging and age‐related diseases

P Davalli, T Mitic, A Caporali… - … medicine and cellular …, 2016 - Wiley Online Library
The aging process worsens the human body functions at multiple levels, thus causing its
gradual decrease to resist stress, damage, and disease. Besides changes in gene …

Use of biomarkers for assessing radiation injury and efficacy of countermeasures

VK Singh, VL Newman, PLP Romaine… - Expert review of …, 2016 - Taylor & Francis
Several candidate drugs for acute radiation syndrome (ARS) have been identified that have
low toxicity and significant radioprotective and radiomitigative efficacy. Inasmuch as …

Dextran-coated cerium oxide nanoparticles: a computed tomography contrast agent for imaging the gastrointestinal tract and inflammatory bowel disease

PC Naha, JC Hsu, J Kim, S Shah, M Bouché… - ACS …, 2020 - ACS Publications
Computed tomography (CT) is an X-ray-based medical imaging technique commonly used
for noninvasive gastrointestinal tract (GIT) imaging. Iodine-and barium-based CT contrast …

Analysis of lncRNA-miRNA-mRNA expression pattern in heart tissue after total body radiation in a mouse model

MJ Aryankalayil, S Martello, MA Bylicky… - Journal of Translational …, 2021 - Springer
Background Radiation therapy is integral to effective thoracic cancer treatments, but its
application is limited by sensitivity of critical organs such as the heart. The impacts of acute …

Radiation-induced long noncoding RNAs in a mouse model after whole-body irradiation

MJ Aryankalayil, S Chopra, J Levin, I Eke… - Radiation …, 2018 - meridian.allenpress.com
Long noncoding RNAs (lncRNAs) are emerging as key molecules in regulating many
biological processes and have been implicated in development and disease pathogenesis …

Redox regulation and noncoding RNAs

MS Leisegang, K Schröder… - Antioxidants & Redox …, 2018 - liebertpub.com
Significance: RNA is a heterogeneous class of molecules with the minority being protein
coding. Noncoding RNAs (ncRNAs) are involved in translation and epigenetic control …

Autophagy-regulating microRNAs: potential targets for improving radiotherapy

H Li, X Jin, B Chen, P Li, Q Li - Journal of cancer research and clinical …, 2018 - Springer
Background Radiotherapy (RT) is one of the most important therapeutic strategies against
cancer. However, resistance of cancer cells to radiation remains a major challenge for RT …

Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection

Y Hu, G Song, F Zhang, N Zhang, F Wang, J Wang… - Iscience, 2023 - cell.com
A better understanding of the molecular mechanism involving the lncRNA-miRNA-mRNA
network underlying radiation damage can be beneficial for radioprotection. This study was …

Early biomarkers associated with P53 signaling for acute radiation injury

W Li, S Zhou, M Jia, X Li, L Li, Q Wang, Z Qi, P Zhou… - Life, 2022 - mdpi.com
Accurate dose assessment within 1 day or even 12 h after exposure through current
methods of dose estimation remains a challenge, in response to a large number of …

DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging

WH Lee, PK Nguyen, D Fleischmann… - European heart …, 2016 - academic.oup.com
The use of diagnostic imaging and image-guided interventions using low-dose ionizing
radiation has increased dramatically in recent years. This is explained by dramatic advances …