Microfluidics opened the possibility to model the physiological environment by controlling
fluids flows, and therefore nutrients supply. It allows to integrate external stimuli such as …

The maintenance of body homeostasis relies heavily on physiological barriers. Dysfunction
of these barriers can lead to various pathological processes, including increased exposure …

The human corneal epithelial barrier plays a crucial role in drug testing studies, including
drug absorption, distribution, metabolism, and excretion (ADME), as well as toxicity testing …

Human skeletal muscles are characterized by a unique aligned microstructure of myotubes
which is important for their function as well as for their homeostasis. Thus, the recapitulation …

Dry eye syndrome (DES) is a complex ocular condition characterized by an unstable tear
film and inadequate tear production, leading to tissue damage. Despite its common …

Abstract According to the World Health Organization, corneal blindness constitutes 5.1% of
global blindness population. Surgical outcomes have been improved significantly in the …

Corneal nerve wounding often causes abnormalities in the cornea and even blindness in
severe cases. In this study, we construct a dorsal root ganglion-corneal stromal cell (DRG …

Corneal endothelial dysfunction is a leading cause of vision loss globally, frequently
requiring corneal transplantation. However, the limited availability of donor tissues …

Intravitreal injection of chemotherapy drugs for intraocular retinoblastoma, for the prevalent
pediatric malignancy treatment with the side effects of severe infection. This study tried to …

Corneal epithelial cells derived from human pluripotent stem cells (hPSCs) are an important
cell source for preclinical models to test ophthalmic drugs. However, current differentiation …