Viscoelastic microfluidics: Progress and challenges

J Zhou, I Papautsky - Microsystems & Nanoengineering, 2020 - nature.com
The manipulation of cells and particles suspended in viscoelastic fluids in microchannels
has drawn increasing attention, in part due to the ability for single-stream three-dimensional …

Flow cytometry: the next revolution

JP Robinson, R Ostafe, SN Iyengar, B Rajwa, R Fischer - Cells, 2023 - mdpi.com
Unmasking the subtleties of the immune system requires both a comprehensive knowledge
base and the ability to interrogate that system with intimate sensitivity. That task, to a …

A Review of Carbapenem Resistance in Enterobacterales and Its Detection Techniques

O Caliskan-Aydogan, EC Alocilja - Microorganisms, 2023 - mdpi.com
Infectious disease outbreaks have caused thousands of deaths and hospitalizations, along
with severe negative global economic impacts. Among these, infections caused by …

Proteins and antibodies in serum, plasma, and whole blood—size characterization using asymmetrical flow field-flow fractionation (AF4)

M Leeman, J Choi, S Hansson, MU Storm… - Analytical and …, 2018 - Springer
The analysis of aggregates of therapeutic proteins is crucial in order to ensure efficacy and
patient safety. Typically, the analysis is performed in the finished formulation to ensure that …

Point-of-care sensors for the management of sepsis

B Reddy Jr, U Hassan, C Seymour, DC Angus… - Nature biomedical …, 2018 - nature.com
Point-of-care sensors that enable the fast collection of information relevant to a patient's
health state can facilitate improved health access, reduce healthcare costs and improve the …

Diagnosis of bloodstream infections: an evolution of technologies towards accurate and rapid identification and antibiotic susceptibility testing

KC Tjandra, N Ram-Mohan, R Abe, MM Hashemi… - Antibiotics, 2022 - mdpi.com
Bloodstream infections (BSI) are a leading cause of death worldwide. The lack of timely and
reliable diagnostic practices is an ongoing issue for managing BSI. The current gold …

[HTML][HTML] Label-free microfluidic sorting of microparticles

J Zhou, P Mukherjee, H Gao, Q Luan… - APL bioengineering, 2019 - pubs.aip.org
Massive growth of the microfluidics field has triggered numerous advances in focusing,
separating, ordering, concentrating, and mixing of microparticles. Microfluidic systems …

Acoustic impedance matched buffers enable separation of bacteria from blood cells at high cell concentrations

P Ohlsson, K Petersson, P Augustsson, T Laurell - Scientific reports, 2018 - nature.com
Sepsis is a common and often deadly systemic response to an infection, usually caused by
bacteria. The gold standard for finding the causing pathogen in a blood sample is blood …

Inertial separation of particles assisted by symmetrical sheath flows in a straight microchannel

T Zhang, DW Inglis, L Ngo, Y Wang… - Analytical …, 2023 - ACS Publications
Over the past two decades, inertial microfluidics, which works at an intermediate range of
Reynolds number (∼ 1< Re<∼ 100), has been widely used for particle separation due to its …

Acoustic separation in plastic microfluidics for rapid detection of bacteria in blood using engineered bacteriophage

P Dow, K Kotz, S Gruszka, J Holder, J Fiering - Lab on a Chip, 2018 - pubs.rsc.org
A more effective treatment of bacteremia requires a diagnostic platform that is both sensitive,
accurate and rapid. Currently, clinical laboratory techniques require growth of bacteria prior …