Uterine cervical carcinoma: role of matrix metalloproteinases

M Libra, A Scalisi, N Vella… - International …, 2009 - spandidos-publications.com
Epidemiological and experimental studies have provided evidence that human
papillomavirus (HPV) infection is a main player in the development of uterine cervical …

Matrix metalloproteinase and its drug targets therapy in solid and hematological malignancies: an overview

AK Chaudhary, S Pandya, K Ghosh… - … Research/Reviews in …, 2013 - Elsevier
Matrix metalloproteinase (MMP) comprises a family of zinc-dependent endopeptidases that
degrade various components of the extracellular matrix (ECM) and basement membrane …

Matrix Metalloproteinase-2 (MMP-2): As an essential factor in cancer progression

RA Reddy, MS Varshini… - Recent Patents on Anti …, 2025 - benthamdirect.com
The development of cancer has been a multistep process involving mutation, proliferation,
survival, invasion, and metastasis. Of all the characteristics of cancer, metastasis is believed …

Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck

AK Chaudhary, M Singh, AC Bharti, K Asotra… - Journal of biomedical …, 2010 - Springer
Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases that are
capable of cleaving all extra cellular matrix (ECM) substrates. Degradation of matrix is a key …

Meta-analysis of association between matrix metalloproteinases 2, 7 and 9 promoter polymorphisms and cancer risk

B Peng, L Cao, X Ma, W Wang, D Wang, L Yu - Mutagenesis, 2010 - academic.oup.com
Abstract Matrix metalloproteinase (MMP) 2, MMP7 and MMP9 are important members of the
MMP family. Four polymorphisms in the promoter region of these MMPs, which are MMP2 …

Association of functional polymorphisms in MMPs genes with gastric cardia adenocarcinoma and esophageal squamous cell carcinoma in high incidence region of …

Y Li, D Sun, Y Duan, X Zhang, N Wang, R Zhou… - Molecular biology …, 2010 - Springer
The aim of the present study was to investigate the association of single nucleotide
polymorphisms (SNPs) in matrix metalloproteinase (MMPs) with the risk of gastric cardia …

Matrix metalloproteinases and genetic mouse models in cancer research: a mini-review

E Wieczorek, E Jablonska, W Wasowicz, E Reszka - Tumor Biology, 2015 - Springer
Carcinogenesis is a multistep and also a multifactorial process that involves agents like
genetic and environmental factors. Matrix metalloproteinases (MMPs) are major proteolytic …

Matrix metalloproteinases in head and neck cancer: current perspectives

I Gkouveris, NG Nikitakis, J Aseervatham… - Metalloproteinases In …, 2017 - Taylor & Francis
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases encoded by 24
distinct genes. Their functions have been implicated in numerous normal and pathologic …

The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction

E Alp, S Menevse, M Tulmac, A Yilmaz… - Genetic testing and …, 2011 - liebertpub.com
The matrix metalloproteinase (MMP) family are key enzymes involved in the breakdown of
the extracellular matrix in normal physiological processes, including tissue remodeling, and …

Matrix metalloproteinase-7 (MMP-7) polymorphism is a risk factor for endometrial cancer susceptibility

YC Yi, PT Chou, LY Chen, WH Kuo… - Clinical chemistry and …, 2010 - degruyter.com
Background: The goal of our study was to evaluate the influence of genetic polymorphisms
of matrix metalloproteinases (MMP)-2, MMP-3 and MMP-7 on susceptibility to endometrial …