Brainstem tumors represent 10–15% of pediatric central nervous system tumors and diffuse
intrinsic pontine glioma (DIPG) is the most common brainstem tumor of childhood. DIPG is …

Diffuse midline gliomas harboring the H3 K27M mutation—including the previously named
diffuse intrinsic pontine glioma (DIPG)—are lethal high-grade pediatric brain tumors that are …

Purpose Diffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median
survival of< 1 year. The International and European Society for Pediatric Oncology DIPG …

BACKGROUND Patients with diffuse midline gliomas (DMGs), including diffuse intrinsic
pontine glioma (DIPG), have dismal outcomes. We previously described the H3. 3K27M …

Purpose of review This review of diffuse intrinsic pontine glioma (DIPG) provides clinical
background, a systematic approach to diagnosis and initial care, and synthesizes historical …

Purpose Diffuse intrinsic pontine glioma (DIPG) is the most aggressive primary pediatric
brain tumor, with< 10% of children surviving 2 years. Radiation therapy (RT) remains the …

Diffuse midline glioma (DMG) is a heterogeneous group of aggressive pediatric brain tumors
with a fatal prognosis. The biological hallmark in the major part of the cases is H3K27 …

Diffuse intrinsic pontine glioma (DIPG) is a type of intrinsic brainstem glial tumor that occurs
primarily in the pediatric population. DIPG is initially diagnosed based on clinical symptoms …

Diffuse intrinsic pontine glioma (DIPG) is a devastating pediatric brain cancer with no
effective therapy. Histological similarity of DIPG to supratentorial high-grade astrocytomas of …

Pediatric diffuse intrinsic pontine glioma (DIPG) represents approximately 20% of all
pediatric CNS tumors. However, disease outcomes are dismal with a median survival of less …