Simple Summary The metabolism of carbohydrates and lipids is essential to meet the
diverse needs of cells. The autophagy cellular pathway is crucial for normal cellular function …

Traditional cancer therapy is mainly targeting on enhancing cell apoptosis, however, it is
well established that many cancer cells are chemo-resistant and defective in apoptosis …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Glutamoptosis is the induction of apoptotic cell death as a consequence of the aberrant
activation of glutaminolysis and mTORC1 signaling during nutritional imbalance in …

Simple Summary Metabolic reprogramming in glioblastoma is a hallmark of malignancy.
Metabolic enzymes and metabolites participate in energetic metabolism and function as …

Ferroptosis is a novel identified form of regulated cell death that has been implied in the
pathology of myocardial infarction (MI). However, the regulation mechanisms of ferroptosis …

Plasmodium falciparum (Pf) is a major cause of human malaria and is transmitted by
infected Anopheles mosquitoes. The initial asymptomatic infection is characterized by …

Colorectal cancer (CRC) is considered as a global major cause of cancer death. Surgical
resection is the main line of treatment; however, chemo-, radiotherapy and other adjuvant …

Over the past two decades, researchers have revealed the crucial functions of glutamine in
supporting the hyperproliferation state of cancer cells. Glutamine acts on maintaining high …

The cellular receptor Notch1 is a central regulator of T‐cell development, and as a
consequence, Notch1 pathway appears upregulated in> 65% of the cases of T‐cell acute …