Architectures of neuronal circuits

L Luo - Science, 2021 - science.org
BACKGROUND The human brain contains about 100 billion neurons, each of which makes
thousands of synaptic connections. Although individual neurons can themselves be …

Development of the vertebrate neuromuscular junction

JR Sanes, JW Lichtman - Annual review of neuroscience, 1999 - annualreviews.org
▪ Abstract We describe the formation, maturation, elimination, maintenance, and
regeneration of vertebrate neuromuscular junctions (NMJs), the best studied of all synapses …

Developmental mechanisms that generate precise patterns of neuronal connectivity

CS Goodman, CJ Shatz - Cell, 1993 - Elsevier
The functioning of the nervous system depends upon the underlying detailed and highly
stereotyped patterns of neuronal connectivity. How these precise patterns of synaptic …

Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance

DM Lin, CS Goodman - Neuron, 1994 - cell.com
We used the enhancer detection/GAL4 system in Drosophila to direct increased levels of
Fasciclin II (Fas II) expression on motoneuron growth cones and axons and to direct ectopic …

Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes

T Tsuchida, M Ensini, SB Morton, M Baldassare… - Cell, 1994 - cell.com
* Howard Hughes Medical Institute Department of Biochemistry and Molecuiar Biophysics
Center for Neurobiology and Behavior Columbia University New York, New York 10032 …

[HTML][HTML] Molecular mechanisms of axon guidance

JK Chilton - Developmental biology, 2006 - Elsevier
In order to form a functional nervous system, neurones extend axons, often over long
distances, to reach their targets. This process is controlled by extracellular receptors and …

The Caenorhabditis elegans gene unc-25encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development

Y Jin, E Jorgensen, E Hartwieg… - Journal of …, 1999 - Soc Neuroscience
The neurotransmitter GABA has been proposed to play a role during nervous system
development. We show that theCaenorhabditis elegans gene unc-25encodes glutamic acid …

Axon guidance and the patterning of neuronal projections in vertebrates

J Dodd, TM Jessell - Science, 1988 - science.org
Over the past decade, new insights have been obtained into the cellular strategies and
molecular mechanisms that guide axons to their targets in the developing vertebrate …

Genes that control neuromuscular specificity in Drosophila

D Van Vactor, H Sink, D Fambrough, R Tsoo… - Cell, 1993 - cell.com
David Van Vactor, Helen Sink, Douglas Fambrough, Rosalie Tsoo, and Corey S. Goodman
Howard Hughes Medical Institute Department of Molecular and Cell Biology University of …

The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance

Z Wills, J Bateman, CA Korey, A Comer, D Van Vactor - Neuron, 1999 - cell.com
Genetic analysis of growth cone guidance choice points in Drosophila identified neuronal
receptor protein tyrosine phosphatases (RPTPs) as key determinants of axon pathfinding …