Global burden, distribution and prevention of β-thalassemias and hemoglobin E disorders

R Colah, A Gorakshakar, A Nadkarni - Expert Review of …, 2010 - Taylor & Francis
The β-thalassemias, including the hemoglobin E disorders, are not only common in the
Mediterranean region, South-East Asia, the Indian subcontinent and the Middle East but …

The spectrum of beta-thalassemia mutations in the 22 Arab countries: a systematic review

AM Khan, AM Al-Sulaiti, S Younes… - Expert Review of …, 2021 - Taylor & Francis
Objectives To investigate the mutational spectrum in the HBB gene in Arab patients with β-
thal. Methods Authors searched five databases (PubMed, Science Direct, Scopus, Web of …

The β-thalassemia mutation spectrum in the Iranian population

H Najmabadi, R Karimi-Nejad, S Sahebjam… - …, 2001 - Taylor & Francis
β-Thalassemia is the most common hereditary disease in Iran. More than two million carriers
of β-thalassemia live in Iran. Since the Iranian population is a mixture of different ethnic …

Molecular and population genetic analyses of β‐Thalassemia in Turkey

GO Tadmouri, Ş Tüzmen, H Özçelik… - American journal of …, 1998 - Wiley Online Library
In this report we describe the molecular analysis of 795 chromosomes derived from
unrelated Turkish β‐thalassemia and sickle cell anemia carriers identified in hematology …

Beta‐Thalassemia in Iran: New Insight into the Role of Genetic Admixture and Migration

AR Rezaee, MM Banoei, E Khalili… - The Scientific World …, 2012 - Wiley Online Library
Iran with an area of 1.648 million km2 is located between the Caspian Sea and the Persian
Gulf. The Iranian population consists of multiethnic groups that have been influenced by …

Abnormal glucose tolerance in Egyptian beta‐thalassemic patients: possible association with genotyping

AS Khalifa, M Salem, E Mounir, MM El‐Tawil… - Pediatric …, 2004 - Wiley Online Library
Background: Type 1 diabetes mellitus (DM) is a frequent complication in patients with beta‐
thalassemia. It is believed to be due to the damage inflicted by iron overload of the …

Geographical distribution of β-globin gene mutations in Syria

H Murad, F Moasses, A Dabboul, Y Mukhalalaty… - …, 2018 - Taylor & Francis
Objectives: β-Thalassemia disease is caused by mutations in the β-globin gene. This is
considered as one of the common genetic disorders in Syria. The aim of this study was to …

A multi-center study in order to further define the molecular basis of β-thalassemia in Thailand, Pakistan, Sri Lanka, Mauritius, Syria, and India, and to develop a simple …

JM Old, SN Khan, I Verma, S Fucharoen… - …, 2001 - Taylor & Francis
The spectrum of the β-thalassemia mutations of Thailand, Pakistan, India, Sri Lanka,
Mauritius and Syria has been further characterized by a multi-center study of 1,235 …

Incidence of haemoglobinopathies in various populations—the impact of immigration

S Henderson, A Timbs, J McCarthy, A Gallienne… - Clinical …, 2009 - Elsevier
OBJECTIVES: The aim of this study was to update the incidence data of beta thalassaemia
mutations in various populations and compare it to the spectrum of mutations in the United …

The molecular analysis of β-thalassemia mutations in Lorestan Province, Iran

AA Kiani, Y Mortazavi, S Zeinali, Y Shirkhani - Hemoglobin, 2007 - Taylor & Francis
β-Thalassemia (thal) is one of the most common genetic disorders in Iran and other
countries. Getting information on the distribution of mutations in different ethnic groups of …