Abstract Introduction The protein Klotho (KL) was first discovered in KL-deficient mice, which
developed a syndrome similar to premature aging in humans. Since then, KL has been …

Background: There is a growing liberalization of cannabis-based preparations for medical
and recreational use. In multiple instances, anxiety and depression are cited as either a …

Cannabinoids and the endocannabinoid system in anxiety, depr... : Current Opinion in
Psychiatry Cannabinoids and the endocannabinoid system in anxiety, depression, and …

Background: The effects of electroconvulsive therapy are usually estimated from changes in
depression scales from studies with relatively small patient samples. Larger patient samples …

Depression is a serious neuropsychiatric disease affecting an increasing number of people
worldwide. Cognitive deficits (including inattention, poor memory, and decision-making …

Current first-line treatments for major depressive disorder (MDD), ie, antidepressant drugs
and psychotherapy, show delayed onset of therapeutic effect as late as 2–3 weeks or more …

Objectives: Evidence points towards an important relationship between the antidepressant
effects of electroconvulsive therapy (ECT) and the modulation of the immune system. To …

The amino-acid tryptophan (TRY) is converted into kynurenine (KYN) and subsequent
metabolites by the tryptophan/catabolites (TRY/CAT) pathway (kynurenine pathway).'Excito …

Amyloid precursor protein and its derivates represent a central factor in the process of
neurodegeneration in Alzheimer's disease (AD). Since mental illnesses share with AD …

Depression is a major mental health disorder, and its pathophysiology is still largely
unknown, as is the action mechanism of electroconvulsive therapy (ECT). Some evidence …