Covalent organic frameworks (COFs) are a class of organic crystalline porous materials
discovered in the early 21st century that have become an attractive class of emerging …

Radical C–H functionalization represents a useful means of streamlining synthetic routes by
avoiding substrate preactivation and allowing access to target molecules in fewer steps. The …

An electrochemically driven nickel-catalyzed enantioselective reductive cross-coupling of
aryl aziridines with alkenyl bromides has been developed, affording enantioenriched β-aryl …

The past decade has witnessed the emergence of N-(acyloxy) phthalimides (NHPI esters)
and its derivatives at the forefront of synthetic methods facilitating the construction of diverse …

The substitution of an alkyl electrophile by a nucleophile is a foundational reaction in
organic chemistry that enables the efficient and convergent synthesis of organic molecules …

Amide alkylation is a fundamental process in organic chemistry. However, the low
nucleophilicity of amides means that divergent coupling with alkyl electrophiles is often not …

The construction of carbon–heteroatom bonds is one of the most active areas of research in
organic chemistry because the function of organic molecules is often derived from the …

Despite the fact that nucleophilic displacement (SN2) of alkyl halides with nitrogen
nucleophiles is one of the first reactions introduced in organic chemistry teaching, its …

Transformation of sterically hindered tertiary alkyl electrophiles under nickel-catalyzed
conditions to forge C (sp3)–C bonds and simultaneously create challenging all-carbon …

Sulfones are common, readily available reagents that have recently attracted attention as
versatile reagents for cross-coupling reactions. This Review summarizes advances in …