Conspectus Ynamides are electron-rich heteroatom-substituted alkynes with a C–C triple
bond directly attached to the amide group. Importantly, this amide group is able to impose an …

Over the past two decades, the development and application of ynamide chemistry have
received more and more attention. Ynamides have proven to be versatile reagents for …

Ynamides are among the most powerful building blocks in organic synthesis and have
become invaluable starting materials for the construction of multifunctional compounds and …

Ynamides consisting of an electron-withdrawing group on the nitrogen atom have proven to
be powerful and versatile building blocks that are involved in a variety of useful chemical …

In the past decades, significant advances have been made on radical Smiles
rearrangement. However, the eventually formed radical intermediates in these reactions are …

Ynamides are special alkynes bearing an electron-withdrawing group on the nitrogen atom,
and they have been extensively studied over the past decade. However, the addition of …

Here, we report a copper‐catalyzed asymmetric cascade cyclization/[1, 2]‐Stevens‐type
rearrangement via a non‐diazo approach, leading to the practical and atom‐economic …

Described herein is a novel Brønsted acid catalyzed intramolecular hydroalkoxylation/
Claisen rearrangement, allowing the practical and atom‐economic synthesis of a range of …

Here an efficient copper‐catalyzed cascade cyclization of azide‐ynamides via α‐imino
copper carbene intermediates is reported, representing the first generation of α‐imino …

Rearrangement reactions have attracted considerable interest over the past decades due to
their high bond-forming efficiency and atom economy in the construction of complex organic …