The activation of a substrate by a chiral catalyst is now regarded as one of the most powerful
strategies that can be employed in the art of asymmetric synthesis. 1 The development of …

Transition-metal-catalyzed reactions have been studied since the very beginning of the past
century and represent a great success in organic chemistry, along with the birth and growth …

The construction of carbon− carbon bonds, along with the creation of stereogenic carbon
centers, continues to be an appealing and demanding area of research, and processes in …

Although chiral mechanically interlocked molecules (MIMs) have been synthesised and
studied, enantiopure examples are relatively under-represented in the pantheon of reported …

The combination of transition metal catalysis and organocatalysis as a new and exciting
research area has attracted increasing attention as it can enable the development of …

The enantioselective synthesis of spirocycles has been a long time pursued dream for
organic chemists. Since the first pioneering efforts of Tamao and coworkers in the …

A domino reaction has been defined by Tietze as a reaction involving two or more bond-
forming transformations that take place under the same reaction conditions, without adding …

The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

In recent years, organocatalysis has enhanced its importance as a tool for the synthesis of
enantiomerically enriched compounds. Among the candidates for organocatalysis, the …

The chemistry of N-heterocyclic carbenes (NHCs) has witnessed tremendous development
in the past two decades: NHCs have not only become versatile ligands for transition metals …