The development of organisms starting from their zygotic state involves a tight integration of
the myriad biochemical signaling interactions with the mechanical forces that eventually …

We discuss some of the practical challenges that one faces in using stochastic
thermodynamics to infer directionality of molecular machines from experimental single …

The cytoskeleton determines cell mechanics and lies at the heart of important cellular
functions. Growing evidence suggests that the manifold tasks of the cytoskeleton rely on the …

Coupling of mechanical forces and chemical transformations is central to the biophysics of
molecular machines, polymer chemistry, fracture mechanics, tribology, and other disciplines …

Proteins control many vital functions in living cells, such as cell growth and cell division.
Reliable coordination of these functions requires the spatial and temporal organization of …

One of the most fascinating features of biological systems is the ability to sustain high
accuracy of all major cellular processes despite the stochastic nature of underlying chemical …

Of all plastics, the most abundantly produced is polyethylene, most of which is destined for
landfills, shipping ports, and natural environments. The limited degradability and …

The observation and manipulation of individual molecules is one of the most exciting
developments in modern molecular science, and the utility of single-molecule methods has …

Chemists visualize chemical reactions as motion along one-dimensional “reaction
coordinates” over free energy barriers. Various rate theories, such as transition state theory …

Major cellular processes are supported by various biomolecular motors that usually operate
together as teams. We present an overview of the collective dynamics of processive …