Aliphatic polycarbonates from cyclic carbonate monomers and their application as biomaterials

W Yu, E Maynard, V Chiaradia, MC Arno… - Chemical …, 2021 - ACS Publications
Aliphatic polycarbonates have gained increased attention as biomaterials largely owing to
their biocompatibility and tunable degradation. Moreover, the ability to introduce functional …

Nanocarrier‐mediated cytosolic delivery of biopharmaceuticals

W He, X Xing, X Wang, D Wu, W Wu… - Advanced functional …, 2020 - Wiley Online Library
Biopharmaceuticals have emerged to play a vital role in disease treatment and have shown
promise in the rapidly expanding pharmaceutical market due to their high specificity and …

Recent advances in targeted nanomedicine as promising antitumor therapeutics

S Hejmady, R Pradhan, A Alexander, M Agrawal… - Drug discovery today, 2020 - Elsevier
Highlights•Nanocarriers with the ability to target tumors are being increasingly explored.•
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …

Folate targeted hybrid lipo-polymeric nanoplexes containing docetaxel and miRNA-34a for breast cancer treatment

S Sharma, S Pukale, DK Sahel, P Singh, A Mittal… - Materials Science and …, 2021 - Elsevier
In spite of established evidence of the synergistic combination of hydrophobic anticancer
molecule and microRNA for breast cancer treatment, their in vivo delivery has not been …

Redox-Sensitive multifunctional hyaluronic acid-based nanomicelles with Fine-controlled anticancer drug release

R Karimi-Soflou, A Karkhaneh - International Journal of Pharmaceutics, 2022 - Elsevier
A significant contributor to cancer-related death globally is metastatic breast cancer. To
reduce death rates, tumor-specific penetration and triggered drug release are crucial …

Emerging roles of low-density lipoprotein in the development and treatment of breast cancer

X Guan, Z Liu, Z Zhao, X Zhang, S Tao, B Yuan… - Lipids in health and …, 2019 - Springer
Breast cancer is a heterogeneous disease with increasing incidence and mortality and
represents one of the most common cancer types worldwide. Low-density lipoprotein (LDL) …

Actively targeted delivery of tamoxifen through stimuli-responsive polymeric nanoparticles for cancer chemotherapy

N Azimijou, R Karimi-Soflou, A Karkhaneh - Journal of Drug Delivery …, 2023 - Elsevier
Cancer has been one of the main healthcare problems, demanding novel therapeutic
approaches to improve treatment efficiency. Chemotherapy is a primary clinical therapeutic …

Intra-articular injection of lornoxicam and microRNA-140 co-loaded cationic liposomes enhanced the therapeutic treatment of experimental osteoarthritis

K He, X Huang, R Shan, X Yang, R Song, F Xie… - Aaps Pharmscitech, 2021 - Springer
Osteoarthritis is a chronic joint disease characterized by chronic inflammation, progressive
destruction of articular cartilage, and subchondral bone sclerosis. When compared to …

Neuroprotective efficacy of co-encapsulated rosiglitazone and vorinostat nanoparticle on streptozotocin induced mice model of Alzheimer disease

S KC, V Kakoty, KV Krishna, SK Dubey… - ACS chemical …, 2021 - ACS Publications
Anomalies in brain insulin signaling have been demonstrated to be involved in the
pathology of Alzheimer disease (AD). In this context, the neuroprotective efficacy of an …

Oral sorafenib-loaded microemulsion for breast cancer: Evidences from the in-vitro evaluations and pharmacokinetic studies

N Chaurawal, C Misra, H Abul Barkat, R Jatyan… - Scientific Reports, 2022 - nature.com
Sorafenib tosylate (SFB) is a multikinase inhibitor that inhibits tumour growth and
proliferation for the management of breast cancer but is also associated with issues like …