Neural stem cell-derived exosomes and regeneration: cell-free therapeutic strategies for traumatic brain injury

L Zhong, J Wang, P Wang, X Liu, P Liu… - Stem Cell Research & …, 2023 - Springer
Regenerative repair of the brain after traumatic brain injury (TBI) remains an extensive
clinical challenge, inspiring intensified interest in therapeutic approaches to explore superior …

Exosomes for angiogenesis induction in ischemic disorders

K Moeinabadi‐Bidgoli, M Rezaee… - Journal of cellular …, 2023 - Wiley Online Library
Ischaemic disorders are leading causes of morbidity and mortality worldwide. While the
current therapeutic approaches have improved life expectancy and quality of life, they are …

Engineered UIO-66 metal-organic framework for delivery of curcumin against breast cancer cells: An in vitro evaluation

S Bazzazan, K Moeinabadi-Bidgoli, ZA Lalami… - Journal of Drug Delivery …, 2023 - Elsevier
Curcumin (Cur) is a traditional herb with known anticancer properties against various
malignancies such as breast cancer. In this study, a metal-organic framework (MOF) based …

Genetic modification and preconditioning strategies to enhance functionality of mesenchymal stromal cells: a clinical perspective

K Moeinabadi-Bidgoli, R Mazloomnejad… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Mesenchymal stromal cell (MSC)-based therapy has generated great hope for
the treatment of various diseases such as myocardial infarction and stroke. Unfortunately …

A spotlight on the interplay between Wnt/β-catenin signaling and circular RNAs in hepatocellular carcinoma progression

A Mafi, H Rismanchi, M Malek Mohammadi… - Frontiers in …, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the deadliest cancers due to multifocal
development and distant metastasis resulting from late diagnosis. Consequently, new …

Drug and gut microbe relationships: moving beyond antibiotics

SV Kumbhare, I Pedroso, JA Ugalde… - Drug Discovery …, 2023 - Elsevier
Our understanding of drug-microbe relationships has evolved from viewing microbes as
mere drug producers to a dynamic, modifiable system where they can serve as drugs or …

[HTML][HTML] Nanomedicine in Neuroprotection, Neuroregeneration, and Blood–Brain Barrier Modulation: A Narrative Review

A Krsek, A Jagodic, L Baticic - Medicina, 2024 - mdpi.com
Nanomedicine is a newer, promising approach to promote neuroprotection,
neuroregeneration, and modulation of the blood–brain barrier. This review includes the …

Anti-cancer effects of human placenta-derived amniotic epithelial stem cells loaded with paclitaxel on cancer cells

A Babajani, A Manzari-Tavakoli, E Jamshidi… - Scientific Reports, 2022 - nature.com
Available therapeutic strategies for cancers have developed side effects, resistance, and
recurrence that cause lower survival rates. Utilizing targeted drug delivery techniques has …

Recent Progress in the Characterization, Synthesis, Delivery Procedures, Treatment Strategies, and Precision of Antimicrobial Peptides

OO Bakare, A Gokul, LA Niekerk, O Aina… - International Journal of …, 2023 - mdpi.com
Infectious diseases are constantly evolving to bypass antibiotics or create resistance against
them. There is a piercing alarm for the need to improve the design of new effective …

Non-coding RNAs in leukemia drug resistance: new perspectives on molecular mechanisms and signaling pathways

A Rahmati, A Mafi, O Vakili, F Soleymani, Z Alishahi… - Annals of …, 2024 - Springer
Like almost all cancer types, timely diagnosis is needed for leukemias to be effectively
cured. Drug efflux, attenuated drug uptake, altered drug metabolism, and epigenetic …