It is well established that microglial form and function are inextricably linked. In recent years,
the traditional view that microglial form ranges between “ramified resting” and “activated …

The natural complexity of the brain, its hierarchical structure, and the sophisticated
topological architecture of the neurons organized in micronetworks and macronetworks are …

Quantification of microglial activation through morphometric analysis has long been a staple
of the neuroimmunologist's toolkit. Microglial morphological phenomics can be conducted …

Tissue engineering is currently one of the most exciting fields in biology (Grayson et al.,
2009). Fractal analysis is equally exciting (Di Ieva et al., 2013), as is the study of microglia …

Fractal analysis in the neurosciences has advanced over the last twenty years to include
measures such as lacunarity. Lacunarity assesses heterogeneity or translational and …

This chapter lays out the elementary principles of fractal geometry underpinning much of the
rest of this book. It assumes a minimal mathematical background, defines the key principles …

Segmentation and analysis of histological images provides a valuable tool to gain insight
into the biology and function of microglial cells in health and disease. Common image …

In this work the properties of ternary systems composed of phosphatidylethanolamines
(PEs), phosphatidylglycerols (PGs) and cardiolipin (CL) were studied with the Langmuir …

In pathological brain, a variety of morphological forms exist that reflect differences in
functional requirements. To better understand microglia function in neurological disease, it is …

Microglia and neurons live physically intertwined, intimately related structurally and
functionally in a dynamic relationship in which microglia change continuously over a much …