For over three decades, a mainstay and goal of clinical oncology has been the development
of therapies promoting the effective elimination of cancer cells by apoptosis. This …

Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Colon cancer affects both men and women and is the world's second most significant cause
of cancer-related mortality. Colon cancer death rates have risen worldwide due to the …

Decades of research have disclosed a plethora of alterations in protein glycosylation that
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …

Long non-coding RNAs (lncRNAs) were, once, viewed as “noise” for transcription. Recently,
many lncRNAs are functionally linked to several human disorders, including cancer. Coiled …

Nuclear factor-κB (NF-κB) has been widely implicated in the development and progression
of cancer. In colorectal cancer (CRC), NF-κB has a key role in cancer-related processes …

The insulin like growth factor (IGF) axis plays a fundamental role in normal growth and
development, and when deregulated makes an important contribution to disease. Here, we …

Colorectal cancer (CRC) is one of the most common types of cancers in humans and is
closely linked to the global cancer-related mortalities worldwide. Molecular pathological …

Objectives The present study aimed at determining the antioxidant activity, total phenols and
flavonoids and to evaluate the antiproliferative activity of ethanolic extract of Matricaria …

Abnormally activated RAS proteins are the main oncogenic driver that governs the
functioning of major signaling pathways involved in the initiation and development of human …