Highlights•We discuss the optimization role in new analytical method development.•We
show in detail the application of experimental designs in analytical chemistry.•Desirability …

The increasing interest in Support Vector Machines (SVMs) over the past 15 years is
described. Methods are illustrated using simulated case studies, and 4 experimental case …

Multivariate calibration has historically been a major cornerstone of chemometrics as
applied to analytical chemistry. However, there are a large number of diverse schools of …

Following the spread of the COVID-19 pandemic crisis, a race was initiated to find a
successful regimen for postinfections. Among those trials, a recent study declared the …

Aqueous-phase photooxidation of glyoxal, a ubiquitous water-soluble gas-phase oxidation
product of many compounds, is a potentially important global and regional source of oxalic …

A novel diffuse reflectance fourier transform infrared spectroscopic method accompanied by
chemometrics was optimized to fulfill the white analytical chemistry and green analytical …

In this work, simultaneous determination of two groups of elements consisting of Pb (II)–Cd
(II) and Cu (II)–Pb (II)–Cd (II) using adsorptive cathodic stripping voltammetry are described …

Four eco-friendly, cost-effective, and fast stability-indicating UV-VIS spectrophotometric
methods were validated for cefotaxime sodium (CFX) determination either in the presence of …

New univariate spectrophotometric method and multivariate chemometric approach were
developed and compared for simultaneous determination of empagliflozin and metformin …

Allura Red, Sunset Yellow, and Tartrazine usually present in commercial soft drinks were
accurately quantified using HLA/GO method, a net analyte signal-based method, without the …