Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …

D Haspula, MA Clark - International journal of molecular sciences, 2020 - mdpi.com
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

Role of cannabinoids in obesity

F Rossi, F Punzo, GR Umano, M Argenziano… - International journal of …, 2018 - mdpi.com
Obesity is an increasing health problem worldwide. Its related comorbidities imply a high
cost for the National Health System and diminish a patient's life quality. Adipose tissue is …

Quality of life and a surveillant endocannabinoid system

RA de Melo Reis, AR Isaac, HR Freitas… - Frontiers in …, 2021 - frontiersin.org
The endocannabinoid system (ECS) is an important brain modulatory network. ECS
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …

Carbon-11: radiochemistry and target-based PET molecular imaging applications in oncology, cardiology, and neurology

NS Goud, A Bhattacharya, RK Joshi… - Journal of Medicinal …, 2021 - ACS Publications
The positron emission tomography (PET) molecular imaging technique has gained its
universal value as a remarkable tool for medical diagnosis and biomedical research …

The Peripheral Cannabinoid Receptor Type 1 (CB1) as a Molecular Target for Modulating Body Weight in Man

SE O'Sullivan, AS Yates, RK Porter - Molecules, 2021 - mdpi.com
The cannabinoid 1 (CB1) receptor regulates appetite and body weight; however, unwanted
central side effects of both agonists (in wasting disorders) or antagonists (in obesity and …

Positron emission tomography imaging of the endocannabinoid system: opportunities and challenges in radiotracer development

L Hou, J Rong, A Haider, D Ogasawara… - Journal of medicinal …, 2020 - ACS Publications
The endocannabinoid system (ECS) is involved in a wide range of biological functions and
comprises cannabinoid receptors and enzymes responsible for endocannabinoid synthesis …

What role does the endocannabinoid system play in the pathogenesis of obesity?

P Schulz, S Hryhorowicz, AM Rychter, A Zawada… - Nutrients, 2021 - mdpi.com
The endocannabinoid system (ECS) is an endogenous signaling system formed by specific
receptors (cannabinoid type 1 and type 2 (CB1 and CB2)), their endogenous ligands …

Combined training increases thermogenic fat activity in patients with overweight and type 2 diabetes

ILP Bonfante, M Monfort-Pires, RG Duft… - International Journal of …, 2022 - nature.com
Background Exercise is an important strategy in the management of diabetes. Experimental
studies have shown that exercise acts, at least in part, by inducing the production of …

Lipid endocannabinoids in energy metabolism, stress and developmental programming

MM Almeida, CP Dias-Rocha, C Calviño… - Molecular and Cellular …, 2022 - Elsevier
The endocannabinoid system (ECS) regulates brain development and function, energy
metabolism and stress in a sex-, age-and tissue-dependent manner. The ECS comprises …

Lipokines and thermogenesis

MD Lynes, SD Kodani, YH Tseng - Endocrinology, 2019 - academic.oup.com
Adaptive thermogenesis is a catabolic process that consumes energy-storing molecules and
expends that energy as heat in response to environmental changes. This process occurs …