[HTML][HTML] The tumor microenvironment and inflammatory breast cancer

A Huang, S Cao, L Tang - Journal of Cancer, 2017 - ncbi.nlm.nih.gov
Inflammatory breast cancer (IBC) is a rare and very aggressive subtype of breast cancer with
clinical manifestations similar to acute inflammation. The prognosis of IBC is still poor even …

S100A proteins as molecular targets in the ocular surface inflammatory diseases

L Tong, W Lan, RR Lim, SS Chaurasia - The ocular surface, 2014 - Elsevier
The S100 proteins are calcium-binding proteins that are exclusively expressed in
vertebrates, where they interact with enzymes, cytoskeletal proteins, receptors, transcription …

[HTML][HTML] Mesenchymal stromal cells inhibit inflammatory lymphangiogenesis in the cornea by suppressing macrophage in a TSG-6-dependent manner

HB Song, SY Park, JH Ko, JW Park, CH Yoon, DH Kim… - Molecular Therapy, 2018 - cell.com
The cornea is a transparent tissue devoid of blood and lymphatic vessels. However, various
inflammatory conditions can cause hemangiogenesis and lymphangiogenesis in the cornea …

[HTML][HTML] Proteomics analyses of human optic nerve head astrocytes following biomechanical strain

RS Rogers, M Dharsee, S Ackloo, JM Sivak… - Molecular & Cellular …, 2012 - ASBMB
We investigate the role of glial cell activation in the human optic nerve caused by raised
intraocular pressure, and their potential role in the development of glaucomatous optic …

[HTML][HTML] Vascular smooth muscle cells stimulate platelets and facilitate thrombus formation through platelet CLEC-2: implications in atherothrombosis

O Inoue, K Hokamura, T Shirai, M Osada, N Tsukiji… - PLoS …, 2015 - journals.plos.org
The platelet receptor CLEC-2 is involved in thrombosis/hemostasis, but its ligand,
podoplanin, is expressed only in advanced atherosclerotic lesions. We investigated CLEC-2 …

[HTML][HTML] S100A4 silencing facilitates corneal wound healing after alkali burns by promoting autophagy via blocking the PI3K/Akt/mTOR signaling pathway

Y Wang, G Gao, Y Wu, Y Wang, X Wu… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: This study investigated the role of S100 calcium binding protein A4 (S100A4) in
corneal wound healing and the underlying mechanism of the S100A4-mediated …

[HTML][HTML] Changes in tear biomarker levels in keratoconus after corneal collagen crosslinking

JI Recalde, JA Duran, I Rodriguez-Agirretxe… - Molecular …, 2019 - ncbi.nlm.nih.gov
Purpose The purpose of this work was to analyze the expressions of matrix
metalloproteinase 9 (MMP-9), calcyclin (S100A6), and cystatin S (CST4) in the tears of …

Low concentration of S100A8/9 promotes angiogenesis‐related activity of vascular endothelial cells: bridges among inflammation, angiogenesis, and tumorigenesis?

C Li, S Li, C Jia, L Yang, Z Song… - Mediators of …, 2012 - Wiley Online Library
Previous studies showed that several members of the S100A family are involved in
neovascularization and tumor development. This study checked whether low concentrations …

[HTML][HTML] Gelatin-based membrane containing usnic acid-loaded liposomes: A new treatment strategy for corneal healing

FR da Silva, RO Silva, HM de Castro Oliveira… - Biomedicine & …, 2020 - Elsevier
Purpose To evaluate the safety and potential healing efficacy of the topical ocular
administration of a gelatin membrane containing usnic acid/liposomes (UALs) for corneal …

The S 100A6 calcium‐binding protein regulates endothelial cell‐cycle progression and senescence

L Bao, AF Odell, SL Stephen, SB Wheatcroft… - The FEBS …, 2012 - Wiley Online Library
Endothelial cells regulate many aspects of vascular physiology, including vasculogenesis
and angiogenesis. The S100 family of calcium‐binding proteins regulates many aspects of …