The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

METHODS: We conducted a systematic review and meta-analysis of epidemiological
studies on the association between cigarette smoking and CRC risk published up to …

Colorectal cancer (CRC) is both one of the most common and one of the most preventable
cancers globally, with powerful but strongly missed potential for primary, secondary and …

Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle,
as evidenced historically by migrant studies and recently by extensive epidemiologic …

Colorectal cancer (CRC) is a leading cause of death worldwide, despite progress made in
detection and management through surgery, chemotherapy, radiotherapy, and …

Evidence indicates that diet, nutrition, lifestyle, the environment, the microbiome, and other
exogenous factors have pathogenic roles and also influence the genome, epigenome …

The overall burden of cancer is rapidly increasing worldwide, reflecting not only population
growth and aging, but also the prevalence and spread of risk factors. Gastrointestinal (GI) …

Accumulating evidence indicates that breakdown of the+ protective mucosal barrier of the
gut plays a role in colorectal cancer (CRC) development. Inflammation and oxidative stress …

Breast cancer affects one in seven women worldwide during their lifetime. Widespread
mammographic screening programs and education campaigns allow for early detection of …