Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry

T Cajka, O Fiehn - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …

Plasmodium falciparum: multifaceted resistance to artemisinins

L Paloque, AP Ramadani, O Mercereau-Puijalon… - Malaria journal, 2016 - Springer
Plasmodium falciparum resistance to artemisinins, the most potent and fastest acting anti-
malarials, threatens malaria elimination strategies. Artemisinin resistance is due to mutation …

The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes

BB Guo, SA Bellingham, AF Hill - Journal of Biological Chemistry, 2015 - ASBMB
Prion diseases are a group of transmissible, fatal neurodegenerative disorders associated
with the misfolding of the host-encoded prion protein, PrP C, into a disease-associated form …

Profiling the essential nature of lipid metabolism in asexual blood and gametocyte stages of Plasmodium falciparum

S Gulati, EH Ekland, KV Ruggles, RB Chan… - Cell host & …, 2015 - cell.com
During its life cycle, Plasmodium falciparum undergoes rapid proliferation fueled by de novo
synthesis and acquisition of host cell lipids. Consistent with this essential role, Plasmodium …

The flexibility of Apicomplexa parasites in lipid metabolism

S Shunmugam, CS Arnold, S Dass, NJ Katris… - PLoS …, 2022 - journals.plos.org
Apicomplexa are obligate intracellular parasites responsible for major human infectious
diseases such as toxoplasmosis and malaria, which pose social and economic burdens …

Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans

S Ramakrishnan, M Serricchio, B Striepen… - Progress in Lipid …, 2013 - Elsevier
Lipid metabolism is of crucial importance for pathogens. Lipids serve as cellular building
blocks, signalling molecules, energy stores, posttranslational modifiers, and pathogenesis …

DGDG and glycolipids in plants and algae

B Kalisch, P Dörmann, G Hölzl - Lipids in plant and algae development, 2016 - Springer
Photosynthetic organelles in plants and algae are characterized by the high abundance of
glycolipids, including the galactolipids mono-and digalactosyldiacylglycerol (MGDG, DGDG) …

Evolution of galactoglycerolipid biosynthetic pathways–from cyanobacteria to primary plastids and from primary to secondary plastids

D Petroutsos, S Amiar, H Abida, LJ Dolch… - Progress in lipid …, 2014 - Elsevier
Photosynthetic membranes have a unique lipid composition that has been remarkably well
conserved from cyanobacteria to chloroplasts. These membranes are characterized by a …

The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp.

L Sheiner, AB Vaidya, GI McFadden - Current opinion in microbiology, 2013 - Elsevier
Highlights•Toxoplasma and Plasmodium possess two organelles of endosymbiotic origin:
the apicoplast, and the mitochondrion.•The mitochondrion hosts a complete TCA cycle and …

Light Remodels Lipid Biosynthesis in Nannochloropsis gaditana by Modulating Carbon Partitioning between Organelles

A Alboresi, G Perin, N Vitulo, G Diretto, M Block… - Plant …, 2016 - academic.oup.com
The seawater microalga Nannochloropsis gaditana is capable of accumulating a large
fraction of reduced carbon as lipids. To clarify the molecular bases of this metabolic feature …