The proteome, or collection of proteoforms expressed in a biological system, is dynamic and
heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have …

Recent advancements in mass spectrometry (MS) have revolutionized quantitative
proteomics, with multiplex isotope labeling emerging as a key strategy for enhancing …

Abstract Background Fatty acids (FAs) are essential cellular components and play important
roles in various biological processes. Importantly, FAs produced by microorganisms from …

The identification of thousands of proteins and their relative levels of expression has
furthered understanding of biological processes and disease and stimulated new systems …

Single-cell proteomics is a powerful approach to precisely profile protein landscapes within
individual cells toward a comprehensive understanding of proteomic functions and tissue …

Isobaric chemical tag labeling (eg, TMT) is a commonly used approach in quantitative
proteomics, and quantification is enabled through detection of low-mass reporter ions …

Single-cell omics is critical in revealing population heterogeneity, discovering unique
features of individual cells, and identifying minority subpopulations of interest. As one of the …

Introduction The identification and characterization of glycopeptides through LC-MS/MS and
advanced enrichment techniques are crucial for advancing clinical glycoproteomics …

Glycosylation has a clear role in cancer initiation and progression, with numerous studies
identifying distinct glycan features or specific glycoproteoforms associated with cancer …

Multiplexing enables the monitoring of hundreds to thousands of proteins in quantitative
proteomics analyses and increases sample throughput. In most mass-spectrometry-based …