Adaptive immune receptor repertoire analysis
B cell and T cell receptor repertoires compose the adaptive immune receptor repertoire
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …
[HTML][HTML] Benchmarking solutions to the T-cell receptor epitope prediction problem: IMMREP22 workshop report
Many different solutions to predicting the cognate epitope target of a T-cell receptor (TCR)
have been proposed. However several questions on the advantages and disadvantages of …
have been proposed. However several questions on the advantages and disadvantages of …
Machine learning approaches to TCR repertoire analysis
Y Katayama, R Yokota, T Akiyama… - Frontiers in …, 2022 - frontiersin.org
Sparked by the development of genome sequencing technology, the quantity and quality of
data handled in immunological research have been changing dramatically. Various data …
data handled in immunological research have been changing dramatically. Various data …
Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2
E Antoun, Y Peng, T Dong - Nature Immunology, 2023 - nature.com
Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2 | Nature Immunology Skip
to main content Thank you for visiting nature.com. You are using a browser version with limited …
to main content Thank you for visiting nature.com. You are using a browser version with limited …
[HTML][HTML] T cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibodies and disease severity
BACKGROUND Measuring the immune response to SARS-CoV-2 enables assessment of
past infection and protective immunity. SARS-CoV-2 infection induces humoral and T cell …
past infection and protective immunity. SARS-CoV-2 infection induces humoral and T cell …
Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19
Whereas pathogen-specific T and B cells are a primary focus of interest during infectious
disease, we have used COVID-19 to ask whether their emergence comes at a cost of …
disease, we have used COVID-19 to ask whether their emergence comes at a cost of …
Clonal diversity predicts persistence of SARS-CoV-2 epitope-specific T-cell response
T cells play a pivotal role in reducing disease severity during SARS-CoV-2 infection and
formation of long-term immune memory. We studied 50 COVID-19 convalescent patients …
formation of long-term immune memory. We studied 50 COVID-19 convalescent patients …
Utility of bulk T-cell receptor repertoire sequencing analysis in understanding immune responses to COVID-19
H Kockelbergh, S Evans, T Deng, E Clyne… - Diagnostics, 2022 - mdpi.com
Measuring immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of coronavirus disease 19 (COVID-19), can rely on antibodies, reactive T …
causative agent of coronavirus disease 19 (COVID-19), can rely on antibodies, reactive T …
The T-cell repertoire of Spanish patients with COVID-19 as a strategy to link T-cell characteristics to the severity of the disease
F Marín-Benesiu, L Chica-Redecillas… - Human Genomics, 2024 - Springer
Background The architecture and dynamics of T cell populations are critical in orchestrating
the immune response to SARS-CoV-2. In our study, we used T Cell Receptor sequencing …
the immune response to SARS-CoV-2. In our study, we used T Cell Receptor sequencing …
Interpretable artificial intelligence model for accurate identification of medical conditions using immune repertoire
Underlying medical conditions, such as cancer, kidney disease and heart failure, are
associated with a higher risk for severe COVID-19. Accurate classification of COVID-19 …
associated with a higher risk for severe COVID-19. Accurate classification of COVID-19 …