Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …

Background Temporal lobe epilepsy is a common and frequently intractable seizure
disorder. Its pathogenesis is thought to involve large-scale alterations to the expression of …

MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …

Seizures result from hypersynchronous, abnormal firing of neuronal populations and are the
primary clinical symptom of the epilepsies. Brain tissue from animal models and patients …

Introduction Ischemic stroke-induced inflammation and inflammasome-dependent pyroptotic
neural death cause serious neurological injury. Nano-sized plasma exosomes have …

Epilepsy is the result of a group of transient abnormalities in brain function caused by an
abnormal, highly synchronized discharge of brain neurons. MicroRNA (miRNA) is a class of …

Mesial temporal lobe epilepsy (MTLE) is a particularly devastating form of human epilepsy
with significant incidence of medical intractability. MicroRNAs (miRs) are small, noncoding …

MicroRNA and epilepsy: profiling, functions and potential cl... : Current Opinion in Neurology
MicroRNA and epilepsy: profiling, functions and potential clinical applications : Current …

Epigenetic processes in the brain involve the transfer of information arising from short-lived
cellular signals and changes in neuronal activity into lasting effects on gene expression. Key …

Synaptic downscaling is a homeostatic mechanism that allows neurons to reduce firing rates
during chronically elevated network activity. Although synaptic downscaling is important in …