[HTML][HTML] SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway

RS Hamad, HM Al-Kuraishy, A Alexiou… - Cell Stress and …, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic caused by a novel
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) leading to pulmonary and …

The possible role of nuclear factor erythroid‐2‐related factor 2 activators in the management of Covid‐19

HM Al‐kuraishy, AI Al‐Gareeb… - … of Biochemical and …, 2024 - Wiley Online Library
COVID‐19 is caused by a novel SARS‐CoV‐2 leading to pulmonary and extra‐pulmonary
manifestations due to oxidative stress (OS) development and hyperinflammation. COVID‐19 …

[HTML][HTML] Gut microbiome composition and dynamics in hospitalized covid-19 patients and patients with post-acute covid-19 syndrome

M Brīvība, L Silamiķele, L Birzniece, L Ansone… - International Journal of …, 2024 - mdpi.com
The gut microbiome plays a pivotal role in the modulation of host responses during viral
infections, and recent studies have underscored its significance in the context of coronavirus …

Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinoma

V Ramesh, PN Gollavilli, L Pinna… - EMBO Molecular …, 2023 - embopress.org
The epithelial‐to‐mesenchymal transition (EMT) plays a central role in the development of
cancer metastasis and resistance to chemotherapy. However, its pharmacological treatment …

Sodium butyrate induced neural stem/progenitor cell death in an experimental model of Japanese encephalitis

A Satheesan, S Sharma, A Basu - Metabolic Brain Disease, 2023 - Springer
The anti-inflammatory and neuroprotective effects of short chain fatty acid (SCFA) butyrate
have been explored in a wide array of neurological pathologies. It is a 4-carbon SCFA …

A gutsy performance: the potential for supplementation of short-chain fatty acids to benefit athletic health, exercise performance, and recovery

MLY Ong, CG Green, T Bongiovanni, LM Heaney - Beneficial Microbes, 2023 - brill.com
The gut microbiome is known to play an important role in the day-to-day physiology and
health of the human host. It is, therefore, not surprising that there is interest surrounding the …

The role of nuclear factor Kappa B (NF-κB) in development and treatment of COVID-19

M Gudowska-Sawczuk, B Mroczko - International journal of molecular …, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus
Disease 19 (COVID-19), a disease that has affected more than 500 million people …

Biomarkers of oxidative stress and inflammation in subjects with COVID-19: Characterization and prognosis of the disease

PMV Coronel, IC Pereira, DCLS Basilio… - Microbial …, 2023 - Elsevier
Abstract Coronavirus disease (COVID-19) is an acute respiratory disease caused by the
new coronavirus (SARS-CoV-2) that has spread throughout the world causing millions of …

Gut microbe–host interactions in post-COVID syndrome: a debilitating or restorative partnership?

TPM Scheithauer, RC Montijn, A Mieremet - Gut Microbes, 2024 - Taylor & Francis
Post-COVID syndrome (PCS) patients have reported a wide range of symptoms, including
fatigue, shortness of breath, and diarrhea. Particularly, the presence of gastrointestinal …

Harnessing and delivering microbial metabolites as therapeutics via advanced pharmaceutical approaches

LM Williams, S Cao - Pharmacology & Therapeutics, 2024 - Elsevier
Microbial metabolites have emerged as key players in the interplay between diet, the gut
microbiome, and host health. Two major classes, short-chain fatty acids (SCFAs) and …