Implants with sensing capabilities

M Veletic, EH Apu, M Simic, J Bergsland… - Chemical …, 2022 - ACS Publications
Because of the aging human population and increased numbers of surgical procedures
being performed, there is a growing number of biomedical devices being implanted each …

Deep brain stimulation in movement disorders: from experimental surgery to evidence‐based therapy

P Krack, J Volkmann, G Tinkhauser… - Movement …, 2019 - Wiley Online Library
Deep brain stimulation (DBS) of 3 different targets is the most important therapeutic
innovation of the past 30 years for patients with fluctuating Parkinson's disease (PD) …

A comprehensive approach to Parkinson's disease: Addressing its molecular, clinical, and therapeutic aspects

M Muleiro Alvarez, G Cano-Herrera… - International journal of …, 2024 - mdpi.com
Parkinson's disease (PD) is a gradually worsening neurodegenerative disorder affecting the
nervous system, marked by a slow progression and varied symptoms. It is the second most …

[PDF][PDF] A review on Parkinson's disease treatment

TK Lee, EL Yankee - Neuroimmunol. Neuroinflamm, 2021 - f.oaes.cc
Parkinson's disease (PD) is a neurodegenerative illness and has a common onset between
the ages of 55 and 65 years. There is progressive development of both motor and non-motor …

Review of noninvasive or minimally invasive deep brain stimulation

X Liu, F Qiu, L Hou, X Wang - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Brain stimulation is a critical technique in neuroscience research and clinical application.
Traditional transcranial brain stimulation techniques, such as transcranial magnetic …

A new implantable closed-loop clinical neural interface: first application in Parkinson's disease

M Arlotti, M Colombo, A Bonfanti, T Mandat… - Frontiers in …, 2021 - frontiersin.org
Deep brain stimulation (DBS) is used for the treatment of movement disorders, including
Parkinson's disease, dystonia, and essential tremor, and has shown clinical benefits in other …

Monitoring Parkinson's disease symptoms during daily life: a feasibility study

M Heijmans, JGV Habets, C Herff, J Aarts… - npj Parkinson's …, 2019 - nature.com
Parkinson's disease symptoms are most often charted using the MDS-UPDRS. Limitations of
this approach include the subjective character of the assessments and a discrepant …

Deep brain stimulation programming 2.0: future perspectives for target identification and adaptive closed loop stimulation

F Hell, C Palleis, JH Mehrkens, T Koeglsperger… - Frontiers in …, 2019 - frontiersin.org
Deep brain stimulation has developed into an established treatment for movement disorders
and is being actively investigated for numerous other neurological as well as psychiatric …

Inhibition of NLRP3 inflammasome ameliorates LPS-induced neuroinflammatory injury in mice via PINK1/Parkin pathway

A Wang, G Zhong, M Ying, Z Fang, Y Chen, H Wang… - …, 2024 - Elsevier
Parkinson's disease (PD) is characterized by the severe loss of dopaminergic neurons in the
substantia nigra pars compacta, leading to motor dysfunction. The onset of PD is often …

Artifact characterization and a multipurpose template-based offline removal solution for a sensing-enabled deep brain stimulation device

LH Hammer, RB Kochanski, PA Starr… - Stereotactic and functional …, 2022 - karger.com
Background: The Medtronic “Percept” is the first FDA-approved deep brain stimulation (DBS)
device with sensing capabilities during active stimulation. Its real-world signal-recording …