Ceftriaxone is a beta-lactam antibiotic that increases the expression of the major glutamate
transporter, GLT-1. As such, ceftriaxone ameliorates symptoms across multiple rodent …

To date, there is no cure or disease-modifying agents available for most well-known
neurological disorders. Current therapy is typically focused on relieving symptoms and …

Background and Purpose: This study aimed to investigate the effect of ceftriaxone on
oxidative stress and gap junction protein (connexin 43, Cx-43) expression in …

Ceftriaxone (CTX) exerts a neuroprotective effect by decreasing glutamate excitotoxicity. We
further studied the underlying mechanisms and effects of CTX early post-treatment on …

Evidence indicates a critical role of neuroinflammatory response as an underlying
pathophysiological process in several central nervous system disorders, including …

Aims: This study was done to investigate the potential neuroprotective effect of semaglutide
during endotoxemia in mice. Material and method: 24 adult male Swiss-albino mice aged 8 …

Aims: This study was done to investigate the potential neuroprotective effect of ipragliflozin
during endotoxemia in mice. Materials & Methods: Twenty-four adult male Swiss-albino mice …

Aim: Interruption of blood flow may result in considerable tissue damage via
ischemia/reperfusion (I/R) injury-induced oxidative stress in brain tissues. The aim of the …

Ischemia–reperfusion (IRI) is a complex physiopathological mechanism involving a large
number of metabolic processes that can eventually lead to cell apoptosis and ultimately …

Objective (s): Ceftriaxone (Cef), a beta-lactam antibiotic, is accompanied by antioxidant and
anti-inflammatory properties. It has been shown that Cef has beneficial effects on …