Immunochemistry in the work‐up of mesothelioma and its differential diagnosis and mimickers

WS Mneimneh, Y Jiang, A Harbhajanka… - Diagnostic …, 2021 - Wiley Online Library
The differential diagnosis in cellular effusions with cytological atypia often includes
malignant mesothelioma (MM), reactive mesothelial proliferation, and malignancies of …

The role of liquid‐based cytology and ancillary techniques in pleural and pericardic effusions: an institutional experience

ED Rossi, T Bizzarro, F Schmitt… - Cancer …, 2015 - Wiley Online Library
BACKGROUND Fine‐needle aspiration cytology (FNAC) of serous membrane effusions may
fulfil a challenging role in the diagnostic analysis of both primary and metastatic disease …

Yield of peritoneal cytology in staging patients with gastric and gastroesophageal cancer

CJ Allen, TE Newhook, TJ Vreeland… - Journal of surgical …, 2019 - Wiley Online Library
Background Guidelines for gastric and gastroesophageal (GE) cancer recommend staging
laparoscopy (SL) with peritoneal cytology (PC). However, the reliability of PC is unknown …

Utility of Claudin-4 versus BerEP4 and B72. 3 in pleural fluids with metastatic lung adenocarcinoma

A Patel, AC Borczuk, MT Siddiqui - Journal of the American Society of …, 2020 - Elsevier
Introduction Lung adenocarcinoma (LADC) is the most common occult primary in patients
presenting with a malignant pleural effusion. Distinguishing metastatic LADC from reactive …

Claudin‐4 immunocytochemistry is specific and sensitive for the diagnosis of malignant carcinomatous effusions: Results from a pilot study

V Hruaii, B Thirunavukkarasu, V Prabha… - Diagnostic …, 2024 - Wiley Online Library
Background Claudin‐4, a tight junction associated protein expressed in epithelial cells, is
purported as a highly specific and sensitive marker for epithelial malignancies. Our aim was …

Immunocytochemical utility of claudin‐4 versus those of Ber‐EP4 and MOC‐31 in effusion cytology

T Oda, S Ogata, S Kawaguchi, S Minabe… - Diagnostic …, 2016 - Wiley Online Library
Background Recently, claudin‐4 (CL4) immunocytochemistry was reported to be useful for
differential diagnosis in effusion cytology. We wondered whether CL4 might be useful for …

The role of liquid based cytology and ancillary techniques in the peritoneal washing analysis: our institutional experience

E Rossi, T Bizzarro, M Martini, A Longatto-Filho… - PLoS …, 2017 - journals.plos.org
Background The cytological analysis of peritoneal effusions serves as a diagnostic and
prognostic aid for either primary or metastatic diseases. Among the different cytological …

Claudin-10 is a new candidate prognostic marker in metastatic high-grade serous carcinoma

B Davidson, D Doutel, A Holth, DA Nymoen - Virchows Archiv, 2023 - Springer
The objective of this study was to analyze the expression and prognostic role of the tight
junction protein claudin-10 in high-grade serous carcinoma (HGSC). Claudin-10 protein …

Diagnostic usefulness of claudin-3 and claudin-4 for immunocytochemical differentiation between metastatic adenocarcinoma cells and reactive mesothelial cells in …

NI Kim, GE Kim, JS Lee - Acta Cytologica, 2016 - karger.com
Abstract Objective: Claudin-3 and claudin-4 have recently been reported as promising
targets for the detection and diagnosis of cancer. This study was designed to evaluate the …

[HTML][HTML] Immunocytochemistry of effusions: Processing and commonly used immunomarkers

VB Shidham, B Janikowski - CytoJournal, 2022 - ncbi.nlm.nih.gov
Definitive cytopathological interpretation of some of the effusion fluids may not be possible
based on cytomorphological evaluation alone. As discussed in other reviews, this is due to …