Natural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …

Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …

Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like
receptors (KIRs) and their interactions with HLA class I molecules. As KIR expression in a …

Abstract Systems-based based approaches have begun to shed light on extrinsic factors that
contribute to immune system variation. Among these, CMV (HHV-5, a β-herpesvirus) …

The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

Natural killer (NK) cells are immune cells that play a crucial role against viral infections and
tumors. To be tolerant against healthy tissue and simultaneously attack infected cells, the …

NK cells offer a first line of defense against viruses and are considered beneficial to the host
during infection. Nevertheless, little is understood regarding the phenotype and function of …

Cytomegaloviruses (CMVs) are highly prevalent, persistent human pathogens that not only
evade but also shape our immune responses. Natural killer (NK) cells play an important role …

Natural killer (NK) cells mediate innate defense against viral infections, but the mechanisms
in place to access their functions as needed during diverse challenges while limiting …

The ability of cells of the immune system to acquire features such as increased longevity and
enhanced secondary responses was long thought to be restricted to cells of the adaptive …