Hindbrain induction and patterning during early vertebrate development

D Frank, D Sela-Donenfeld - Cellular and molecular life sciences, 2019 - Springer
The hindbrain is a key relay hub of the central nervous system (CNS), linking the bilaterally
symmetric half-sides of lower and upper CNS centers via an extensive network of neural …

Axonal projection patterns of the dorsal interneuron populations in the embryonic hindbrain

D Hirsch, A Kohl, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Unraveling the inner workings of neural circuits entails understanding the cellular origin and
axonal pathfinding of various neuronal groups during development. In the embryonic …

The gelatinases, matrix metalloproteinases 2 and 9, play individual roles in skeleton development

R Kalev-Altman, JN Janssen, N Ben-Haim, T Levy… - Matrix Biology, 2022 - Elsevier
The gelatinases, a subgroup of the matrix metalloproteinases (MMPs) superfamily are
composed of two members; MMP2 and MMP9. They are known to degrade gelatin among …

A new role of hindbrain boundaries as pools of neural stem/progenitor cells regulated by Sox2

Y Peretz, N Eren, A Kohl, G Hen, K Yaniv, K Weisinger… - BMC biology, 2016 - Springer
Background Compartment boundaries are an essential developmental mechanism
throughout evolution, designated to act as organizing centers and to regulate and localize …

[PDF][PDF] A new role of the membrane-type matrix metalloproteinase 16 (MMP16/MT3-MMP) in neural crest cell migration

L Roth, R Kalev-Altman, E Monsonego-Ornan… - Int J Dev …, 2017 - academia.edu
Neural crest cells (NCCs) are a transient population of neuroectodermal-originated cells that
populate the dorsal neural tube (dNT), before migrating and giving rise to multiple cell …

[HTML][HTML] β1-integrin deletion from the lens activates cellular stress responses leading to apoptosis and fibrosis

Y Wang, AM Terrell, BA Riggio, D Anand… - … & Visual Science, 2017 - tvst.arvojournals.org
Purpose: Previous research showed that the absence of β1-integrin from the mouse lens
after embryonic day (E) 13.5 (β1MLR10) leads to the perinatal apoptosis of lens epithelial …

Hox proteins drive cell segregation and non-autonomous apical remodelling during hindbrain segmentation

F Prin, P Serpente, N Itasaki, AP Gould - Development, 2014 - journals.biologists.com
Hox genes encode a conserved family of homeodomain transcription factors regulating
development along the major body axis. During embryogenesis, Hox proteins are expressed …

Storage temperature dictates the ability of chicken embryos to successfully resume development by regulating expression of blastulation and gastrulation genes

N Pokhrel, O Genin, D Sela-Donenfeld… - Frontiers in …, 2022 - frontiersin.org
The avian embryo has a remarkable ability that allows it to suspend its development during
blastulation for a long time at low temperatures, and to resume normal development when …

Temporal-specific roles of fragile X mental retardation protein in the development of the hindbrain auditory circuit

X Wang, A Kohl, X Yu, DAR Zorio, A Klar… - …, 2020 - journals.biologists.com
Fragile X mental retardation protein (FMRP) is an RNA-binding protein abundant in the
nervous system. Functional loss of FMRP leads to sensory dysfunction and severe …

Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development

M Maguire, MC Larsen, CM Vezina, L Quadro… - PLoS …, 2020 - journals.plos.org
Background Cytochrome P450 1b1 (Cyp1b1) deletion and dietary retinol deficiency during
pregnancy (GVAD) affect perinatal liver functions regulated by Srebp. Cyp1b1 is not …