Ginkgolides-loaded soybean phospholipid-stabilized nanosuspension with improved storage stability and in vivo bioavailability

P Wang, X Cao, Y Chu - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevier
The purpose of this study was to investigate the effects of soybean phospholipid, as a steric
stabilizer, on improving dissolution rate, storage stability and bioavailability of ginkgolides …

Solid dispersion pellets: an efficient pharmaceutical approach to enrich the solubility and dissolution rate of deferasirox

A Farmoudeh, A Rezaeiroshan… - BioMed research …, 2020 - Wiley Online Library
Deferasirox (DFX) is an oral iron‐chelating agent and classified into class II of the
Biopharmaceutics Classification System. Low bioavailability of the drug due to insufficient …

Evaluation of experimental multi-particulate polymer-coated drug delivery systems with meloxicam

M Hîrjău, DS Miron, V Anuța, D Lupuliasa, MV Ghica… - Coatings, 2020 - mdpi.com
The objectives of this study are the development and evaluation of modified release multi-
particulate drug delivery systems containing a BCS class II drug (meloxicam), formulated as …

Enteric coating process of diclofenac sodium pellets in a fluid bed coater with a wurster insert: Influence of process variables on coating performance and release …

R Albanez, M Nitz, OP Taranto - Advanced Powder Technology, 2013 - Elsevier
The objective of this work was to study the coating process of diclofenac sodium pellets, with
the commercial aqueous coating suspension for enteric release–Acryl-Eze® MP, in a fluid …

Investigation on influence of Wurster coating process parameters for the development of delayed release minitablets of Naproxen

N Shah, T Mehta, R Aware, V Shetty - Drug Development and …, 2017 - Taylor & Francis
The present work aims at studying process parameters affecting coating of minitablets (3 mm
in diameter) through Wurster coating process. Minitablets of Naproxen with high drug …

Improved dissolution rate and bioavailability of fenofibrate pellets prepared by wet-milled-drug layering

P Wang, Q Luo, Y Miao, L Ying, H He… - Drug development and …, 2012 - Taylor & Francis
Objective: The objective of this study is to investigate the wet-milled-drug layering process
which could significantly improve the dissolution rate and oral bioavailability of fenofibrate …

Excipients and their functionality for enabling technologies in oral dosage forms

S Thakkar, K Sharma, S Khurana… - … , and Applications in …, 2016 - Wiley Online Library
Over the years, excipients have undergone a paradigm shift from being “inert ingredients” to
“functional ingredients” in a dosage form. Excipients are being increasingly used to enhance …

Influence of the type of enteric coating suspension, coating layer and process conditions on dissolution profile and stability of coated pellets of diclofenac sodium

R Albanez, M Nitz, OP Taranto - Powder technology, 2015 - Elsevier
In this work, diclofenac sodium pellets were produced through an extrusion/spheronization
process and subsequently coated in a fluidized bed coater column with a Wurster insert. The …

Comparative dissolution study of drug and inert isomalt based core material from layered pellets

N Kállai-Szabó, O Luhn, J Bernard… - … of Pharmaceutical and …, 2014 - Elsevier
Layered and coated pellets were formulated to control the release of the diclofenac sodium
selected as model drug. A highly water soluble isomalt inert pellet core material was used to …

Overview of drug product development

P Narayan - Current Protocols in Pharmacology, 2011 - Wiley Online Library
The process for developing drug delivery systems has evolved over the past two decades
with more scientific rigor, involving a collaboration of various fields, ie, biology, chemistry …