Natural products: potential treatments for cisplatin-induced nephrotoxicity

C Fang, D Lou, L Zhou, J Wang, B Yang, Q He… - Acta Pharmacologica …, 2021 - nature.com
Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment
of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer …

[HTML][HTML] The effects of natural and synthetic blue dyes on human health: A review of current knowledge and therapeutic perspectives

B Olas, J Białecki, K Urbańska, M Bryś - Advances in Nutrition, 2021 - Elsevier
Blue synthetic dyes are widely used in many industries. Although they are approved for use
as food dyes and in cosmetics and some medicines, their impacts on consumer health …

Genipin, an inhibitor of UCP2 as a promising new anticancer agent: a review of the literature

YS Cho - International Journal of Molecular Sciences, 2022 - mdpi.com
Genipin is a protein cross-linking agent extracted from Gardenia (Gardenia jasminoides
Ellis) fruits. This fruit has conventionally been used as a Chinese herbal medicine for the …

Cannabidiol overcomes oxaliplatin resistance by enhancing NOS3-and SOD2-induced autophagy in human colorectal cancer cells

S Jeong, BG Kim, DY Kim, BR Kim, JL Kim, SH Park… - Cancers, 2019 - mdpi.com
Although oxaliplatin is an effective chemotherapeutic drug for colorectal cancer (CRC)
treatment, patients often develop resistance to it. Therefore, a new strategy for CRC …

Properties and molecular mechanisms underlying geniposide-mediated therapeutic effects in chronic inflammatory diseases

D Ran, W Hong, W Yan, W Mengdie - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Geniposide (GE) is ubiquitous in nearly 40 species of
plants, among which Gardenia jasminoides J. Ellis has the highest content, and has been …

Genipin promotes the apoptosis and autophagy of neuroblastoma cells by suppressing the PI3K/AKT/mTOR pathway

X Liu, C Zhou, B Cheng, Y Xiong, Q Zhou, E Wan… - Scientific Reports, 2024 - nature.com
This study investigated the underlying function and mechanism of genipin in neuroblastoma
(NB). Using flow cytometry analysis and cytotoxicity tests, in vitro studies were conducted to …

miR‐200b‐3p mitigates oxaliplatin resistance via targeting TUBB3 in colorectal cancer

YZ Wu, HY Lin, Y Zhang… - The journal of gene …, 2020 - Wiley Online Library
Background Numerous abnormally expressed miRs have been reported involved in
oxaliplatin (L‐OHP) resistance of colorectal cancer (CRC). The present study aimed to …

The preventive and therapeutic potential of native Brazilian fruits on colorectal cancer

RP do Nascimento, LM Reguengo… - Food Bioscience, 2022 - Elsevier
In the last years, colorectal cancer (CRC) has been increasing substantially in developing
countries. While the consumption of fat and meat have been linked with increased CRC risk …

Impact of digestive inflammatory environment and genipin crosslinking on immunomodulatory capacity of injectable musculoskeletal tissue scaffold

C Shortridge, E Akbari Fakhrabadi… - International Journal of …, 2021 - mdpi.com
The paracrine and autocrine processes of the host response play an integral role in the
success of scaffold-based tissue regeneration. Recently, the immunomodulatory scaffolds …

Synergistic antitumor effect of Andrographolide and cisplatin through ROS-mediated ER stress and STAT3 inhibition in colon cancer

H Hong, W Cao, Q Wang, C Liu, C Huang - Medical Oncology, 2022 - Springer
Colon cancer is one of the most leading death-causing cancers in the world. Cisplatin has
been widely used as the first-line treatment of cancer. However, its clinical application is …