Background The present review is part of the ESCMID Study Group for Infections in
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …

Helminth parasites infect an alarmingly large proportion of the world's population, primarily
within tropical regions, and their ability to down‐modulate host immunity is key to their …

Elevated serum IgE levels are associated with allergic disorders, parasitosis and specific
immunologic abnormalities. In addition, epidemiological and mechanistic evidence indicates …

The hygiene hypothesis was proposed almost three decades ago. Nevertheless, its
mechanism still remains with relevant controversies. Some studies defend that early …

Helminth parasites are highly prevalent in many low-and middle-income countries, in which
inflammatory bowel disease and other immunopathologies are less frequent than in the …

The microbiota inhabits the gastrointestinal tract, providing essential capacities to the host.
The microbiota is a crucial factor in intestinal health and regulates intestinal physiology …

The IL-33-ST2 pathway is an important initiator of type 2 immune responses. We previously
characterised the HpARI protein secreted by the model intestinal nematode …

Filariae are vector-borne parasitic nematodes that are endemic worldwide, in tropical and
subtropical regions. Important human filariae spp. include Onchocerca volvulus, Wuchereria …

This study investigates the relationship between helminth infection and allergic sensitization
by assessing the influence of preexisting allergy on the outcome of helminth infections …

Experimental and epidemiological evidence shows that parasites, particularly helminths,
play a central role in balancing the host immunity. It was demonstrated that parasites can …