Porcine rotaviruses: epidemiology, immune responses and control strategies
Rotaviruses (RVs) are a major cause of acute viral gastroenteritis in young animals and
children worldwide. Immunocompetent adults of different species become resistant to …
children worldwide. Immunocompetent adults of different species become resistant to …
Strategies for design and application of enteric viral vaccines
Enteric viral infections in domestic animals cause significant economic losses. The recent
emergence of virulent enteric coronaviruses [porcine epidemic diarrhea virus (PEDV)] in …
emergence of virulent enteric coronaviruses [porcine epidemic diarrhea virus (PEDV)] in …
Pathogenesis of a genogroup II human norovirus in gnotobiotic pigs
We evaluated the gnotobiotic (Gn) pig as a model to study the pathogenesis of human
norovirus (HuNoV) and to determine the target cells for viral replication. Sixty-five Gn pigs …
norovirus (HuNoV) and to determine the target cells for viral replication. Sixty-five Gn pigs …
Cellular and humoral immunity following Snow Mountain virus challenge
Little is known about the immune response to noroviruses. To elucidate the immunobiology
of norovirus infection in humans, 15 volunteers were challenged with Snow Mountain virus …
of norovirus infection in humans, 15 volunteers were challenged with Snow Mountain virus …
VP8 Mosaic Nanoparticles Elicit Cross-Neutralizing Immune Responses and Provide Protection Against Heterotypic Rotavirus Challenge in Mice
F Song, Y Zeng, R Sheng, Y Lin, X Wang, C Hong… - ACS …, 2024 - ACS Publications
Group A rotaviruses (RVA) remain one of the dominant pathogens causing diarrhea in
children under 5 years of age worldwide, despite a sharp decrease of RVA-associated …
children under 5 years of age worldwide, despite a sharp decrease of RVA-associated …
Adjuvants modulating mucosal immune responses or directing systemic responses towards the mucosa
E Cox, F Verdonck, D Vanrompay, B Goddeeris - Veterinary research, 2006 - hal.science
In developing veterinary mucosal vaccines and vaccination strategies, mucosal adjuvants
are one of the key players for inducing protective immune responses. Most of the mucosal …
are one of the key players for inducing protective immune responses. Most of the mucosal …
Immunogenicity and protective efficacy of rotavirus 2/6-virus-like particles produced by a dual baculovirus expression vector and administered intramuscularly …
A Bertolotti-Ciarlet, M Ciarlet, SE Crawford, ME Conner… - Vaccine, 2003 - Elsevier
Virus-like particles (VLPs) are being evaluated as a candidate rotavirus vaccine. Rotavirus
VLPs composed of simian SA11 strain VP2 and VP6 proteins (homologous 2/6-VLPs) were …
VLPs composed of simian SA11 strain VP2 and VP6 proteins (homologous 2/6-VLPs) were …
Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus
MSP Azevedo, L Yuan, S Pouly, AM Gonzales… - Journal of …, 2006 - Am Soc Microbiol
To understand the role of cytokines during rotavirus infection, we assessed the kinetics of
tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6)(proinflammatory), IL-12 (Th1 …
tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6)(proinflammatory), IL-12 (Th1 …
Induction of mucosal immune responses and protection against enteric viruses: rotavirus infection of gnotobiotic pigs as a model
Enteric viruses are a major cause of diarrhea in animals and humans. Among them,
rotaviruses are one of the most important causes of diarrhea in young animals and human …
rotaviruses are one of the most important causes of diarrhea in young animals and human …
Viremia and nasal and rectal shedding of rotavirus in gnotobiotic pigs inoculated with Wa human rotavirus
MS Azevedo, L Yuan, KI Jeong, A Gonzalez… - Journal of …, 2005 - Am Soc Microbiol
Respiratory symptoms with rotavirus shedding in nasopharyngeal secretions have been
reported in children with and without gastrointestinal symptoms (Zheng et al., 1991, J. Med …
reported in children with and without gastrointestinal symptoms (Zheng et al., 1991, J. Med …