Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors
Abstract Treatment with immune checkpoint inhibitors (ICI) has demonstrated clinical benefit
for a wide range of cancer types. Because only a subset of patients experience clinical …
for a wide range of cancer types. Because only a subset of patients experience clinical …
Inflammatory markers in cancer immunotherapy
Simple Summary Inflammation has been recognized to be linked to tumor development.
Several markers of inflammation can be detected via blood such as variety of blood cells …
Several markers of inflammation can be detected via blood such as variety of blood cells …
Focus on the dynamics of neutrophil-to-lymphocyte ratio in cancer patients treated with immune checkpoint inhibitors: a meta-analysis and systematic review
Simple Summary Neutrophil-to-lymphocyte ratio (NLR) as a prognostic indicator of patients
treated with immunotherapy has been fully reported. However, the dynamics of NLR after …
treated with immunotherapy has been fully reported. However, the dynamics of NLR after …
Association between systemic immune-inflammation index and diabetic depression
J Wang, D Zhou, Z Dai, X Li - Clinical interventions in aging, 2021 - Taylor & Francis
Background Depression is highly prevalent in patients with diabetes mellitus (DM). Diabetic
depression has been shown to be associated with low-grade systemic inflammation. In …
depression has been shown to be associated with low-grade systemic inflammation. In …
Diagnostic value of peripheral hematologic markers for coronavirus disease 2019 (COVID‐19): a multicenter, cross‐sectional study
J Peng, D Qi, G Yuan, X Deng, Y Mei… - Journal of clinical …, 2020 - Wiley Online Library
Background To determine the diagnostic value of hematologic markers for coronavirus
disease 2019 (COVID‐19) and explore their relationship with disease severity. Methods …
disease 2019 (COVID‐19) and explore their relationship with disease severity. Methods …
Predictive value of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in advanced hepatocellular carcinoma patients treated with anti–PD‐1 therapy
S Dharmapuri, U Özbek, JY Lin, M Sung… - Cancer …, 2020 - Wiley Online Library
Background Currently, there are no recognized or validated biomarkers to identify
hepatocellular carcinoma patients (HCC) likely to benefit from anti–PD‐1 therapy. We …
hepatocellular carcinoma patients (HCC) likely to benefit from anti–PD‐1 therapy. We …
Assessment of systematic inflammatory and nutritional indexes in extensive-stage small-cell lung cancer treated with first-line chemotherapy and atezolizumab
Background The present study aims to investigate the prognostic role of systematic
inflammatory and nutritional indexes in extensive-stage small-cell lung cancer (ES-SCLC) …
inflammatory and nutritional indexes in extensive-stage small-cell lung cancer (ES-SCLC) …
Association of blood biomarkers and autoimmunity with immune related adverse events in patients with cancer treated with immune checkpoint inhibitors
Patients with cancer treated with immune checkpoint inhibitors (ICIs) develop immune
related adverse events (irAEs), however biomarkers are lacking. We hypothesized that …
related adverse events (irAEs), however biomarkers are lacking. We hypothesized that …
Clinical value of neutrophil-to-lymphocyte ratio in patients with non-small-cell lung cancer treated with PD-1/PD-L1 inhibitors
T Jiang, Y Bai, F Zhou, W Li, G Gao, C Su, S Ren… - Lung cancer, 2019 - Elsevier
Introduction There is unmet need to explore the predictive biomarkers of PD-1/PD-L1
inhibitors in patients with non-small-cell lung cancer (NSCLC). Here, we aimed to …
inhibitors in patients with non-small-cell lung cancer (NSCLC). Here, we aimed to …
Impact of sarcopenia, BMI, and inflammatory biomarkers on survival in advanced hepatocellular carcinoma treated with anti-PD-1 antibody
M Akce, Y Liu, K Zakka, DJ Martini… - American Journal of …, 2021 - journals.lww.com
Background: Sarcopenia and inflammation are independently associated with worse
survival in cancer patients. This study aims to determine the impact of sarcopenia, body …
survival in cancer patients. This study aims to determine the impact of sarcopenia, body …